Effectiveness and sequelae of very low-dose suxamethonium for nasal intubation

Br J Anaesth. 1995 Jan;74(1):31-4. doi: 10.1093/bja/74.1.31.

Abstract

We have studied the effectiveness and sequelae of low-dose suxamethonium in 60 day-case oral surgery patients requiring nasal intubation. Anaesthesia was induced with propofol and alfentanil; 60 patients were allocated randomly to three groups of 20 patients and received no suxamethonium, suxamethonium 0.25 mg kg-1 or 0.5 mg kg-1. All patients received i.v. fentanyl and diclofenac 100 mg rectally for analgesia. Good intubating conditions were produced in all 20 patients receiving suxamethonium 0.25 mg kg-1, in 19 patients receiving suxamethonium 0.5 mg kg-1 and in 11 patients not receiving a neuromuscular blocker. The incidence of postoperative myalgia after suxamethonium 0.25 mg kg-1 (20%) did not differ significantly from the incidence after propofol and alfentanil alone (28%).

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Alfentanil
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Intubation, Intratracheal / methods*
  • Male
  • Middle Aged
  • Muscles / drug effects
  • Propofol
  • Succinylcholine / administration & dosage*

Substances

  • Alfentanil
  • Succinylcholine
  • Propofol