This study presents data related to 136 patients who were treated with 300 implants in the edentulous mandible anterior to the mental foramina. Two implant systems were used: the titanium plasma-sprayed screw implant (TPS) and the intramobile cylinder implant (IMZ) in three different modifications. The longest observation time was 11 years, with a mean of 5.7 years. Patients were recalled for regular clinical examinations once every 6 months. After prosthesis placement, only a few implant losses were recorded, although critical states could be found according to periodontal standards. This led to the definition of success criteria according to clinically tolerable bone loss or pocket-probing depths. The 5-year survival rate considering the implant loss was greater than 90% for all implant systems and was lowest for the new type IMZ 3.3. Selecting a vertical bone loss of 4 mm or more as failure criterion reduced the survival rates, which then ranged from 83% to 97% (according to the implant system) for the 5-year interval. The mean annual bone-level change was identified individually for each implant using a linear-regression model.