Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol)

Nature. 1972 Dec 15;240(5381):410-1. doi: 10.1038/240410a0.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Acetaminophen / pharmacology*
  • Animals
  • Aspirin / pharmacology
  • Brain / enzymology*
  • Dogs
  • In Vitro Techniques
  • Indomethacin / pharmacology
  • Ligases / antagonists & inhibitors*
  • Prostaglandins
  • Rabbits
  • Spleen / enzymology

Substances

  • Prostaglandins
  • Acetaminophen
  • Ligases
  • Aspirin
  • Indomethacin