Postnatal growth in preterm infants and later health outcomes: a systematic review

Acta Paediatr. 2015 Oct;104(10):974-86. doi: 10.1111/apa.13128.

Abstract

In preterm infants, poor postnatal growth is associated with adverse neurocognitive outcomes; conversely, rapid postnatal growth is supposedly harmful for future development of metabolic diseases.

Conclusion: In this systematic review, observational studies reported consistent positive associations between postnatal weight or head growth and neurocognitive outcomes; however, there was limited evidence from the few intervention studies. Evidence linking postnatal weight gain to later adiposity and other cardiovascular disease risk factors in preterm infants was also limited.

Keywords: Feeding; Growth velocity; Health; Postnatal; Preterm newborn.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Adiposity
  • Child Development*
  • Humans
  • Infant, Newborn
  • Infant, Premature / growth & development*
  • Insulin Resistance
  • Neurocognitive Disorders / prevention & control
  • Risk Factors