Abstract
In 2010 the Hellenic center for disease control and prevention launched the "Prokroustes" nationwide action plan to tackle the increasing rates of carbapenem resistance among gram-negative nosocomial pathogens. In the present report, data from a Greek tertiary-care hospital are presented three years after the adoption of the infection control measures. Carbapenem resistance rates have been contained for Klebsiella pneumoniae and Acinetobacter baumannii but not for Pseudomonas aeruginosa. More worryingly, in accordance with their overuse against carbapenem-resistant bacteria, resistance rates to colistin and tigecycline have risen significantly.
Keywords:
Carbapenems; Colistin; Infection control; Tigecycline.
MeSH terms
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Acinetobacter Infections / epidemiology
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / drug effects*
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Acinetobacter baumannii / genetics
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Acinetobacter baumannii / isolation & purification
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Anti-Bacterial Agents / pharmacology*
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Carbapenems / pharmacology
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Colistin / pharmacology
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Containment of Biohazards / statistics & numerical data
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Cross Infection / epidemiology
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Cross Infection / microbiology*
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Drug Resistance, Multiple, Bacterial*
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Gentamicins / pharmacology
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Greece / epidemiology
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Humans
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Klebsiella Infections / epidemiology
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / drug effects*
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification
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Microbial Sensitivity Tests
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Minocycline / analogs & derivatives
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Minocycline / pharmacology
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Tertiary Care Centers / statistics & numerical data
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Tigecycline
Substances
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Anti-Bacterial Agents
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Carbapenems
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Gentamicins
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Tigecycline
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Minocycline
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Colistin