Early surgery for patients with a fracture of the hip decreases 30-day mortality

Bone Joint J. 2015 Jan;97-B(1):104-8. doi: 10.1302/0301-620X.97B1.35041.

Abstract

There has been extensive discussion about the effect of delay to surgery on mortality in patients sustaining a fracture of the hip. Despite the low level of evidence provided by many studies, a consensus has been accepted that delay of > 48 hours is detrimental to survival. The aim of this prospective observational study was to determine if early surgery confers a survival benefit at 30 days. Between 1989 and 2013, data were prospectively collected on patients sustaining a fracture of the hip at Peterborough City Hospital. They were divided into groups according to the time interval between admission and surgery. These thresholds ranged from < 6 hours to between 49 and 72 hours. The outcome which was assessed was the 30-day mortality. Adjustment for confounders was performed using multivariate binary logistic regression analysis. In all, 6638 patients aged > 60 years were included. Worsening American Society of Anaesthesiologists grade (p < 0.001), increased age (p < 0.001) and extracapsular fracture (p < 0.019) increased the risk of 30-day mortality. Increasing mobility score (p = 0.014), mini mental test score (p < 0.001) and female gender (p = 0.014) improved survival. After adjusting for these confounders, surgery before 12 hours improved survival compared with surgery after 12 hours (p = 0.013). Beyond this the increasing delay to surgery did not significantly affect the 30-day mortality.

Keywords: 12 hours; 30-day mortality; ASA grade; Early surgery; Hip fracture.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Arthroplasty, Replacement, Hip / methods
  • Confidence Intervals
  • Databases, Factual
  • Emergency Treatment / methods*
  • Female
  • Fracture Fixation, Internal / methods
  • Fracture Fixation, Internal / mortality*
  • Hip Fractures / diagnostic imaging
  • Hip Fractures / mortality*
  • Hip Fractures / surgery*
  • Hospital Mortality
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Ontario
  • Prognosis
  • Prospective Studies
  • Radiography
  • Risk Assessment
  • Survival Rate
  • Time Factors
  • Treatment Outcome