Abstract
In Saudi Arabia, including regions of Riyadh and Al Ahsa, pseudoparticle neutralisation (ppNT) and microneutralisation (MNT) tests detected no antibodies to Middle East Respiratory Syndrome coronavirus (MERS-CoV) in sheep (n= 100), goats (n= 45), cattle (n= 50) and chickens (n= 240). Dromedary camels however, had a high prevalence of MERS-CoV antibodies. Bovine coronavirus (BCoV) infected sera from cattle had no cross-reactivity in MERS-CoV ppNT or MNT, while many dromedary camels’ sera reacted to both BCoV and MERS-CoV. Some nevertheless displayed specific serologic reaction profiles to MERS-CoV.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Neutralizing / blood*
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Antibodies, Viral / blood*
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Camelus / blood
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Case-Control Studies
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Coronavirus / immunology*
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Coronavirus / isolation & purification
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Coronavirus Infections / blood
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Coronavirus Infections / epidemiology*
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Coronavirus Infections / virology
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Female
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Humans
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Livestock / blood
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Male
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Middle Aged
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Middle East
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Prevalence
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Respiratory Tract Infections / blood
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Respiratory Tract Infections / epidemiology*
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Respiratory Tract Infections / virology
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Saudi Arabia / epidemiology
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Seroepidemiologic Studies
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Syndrome
Substances
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Antibodies, Neutralizing
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Antibodies, Viral