Cohort profile: The men androgen inflammation lifestyle environment and stress (MAILES) study

Int J Epidemiol. 2014 Aug;43(4):1040-53. doi: 10.1093/ije/dyt064. Epub 2013 Jun 19.

Abstract

The Men Androgen Inflammation Lifestyle Environment and Stress (MAILES) Study was established in 2009 to investigate the associations of sex steroids, inflammation, environmental and psychosocial factors with cardio-metabolic disease risk in men. The study population consists of 2569 men from the harmonisation of two studies: all participants of the Florey Adelaide Male Ageing Study (FAMAS) and eligible male participants of the North West Adelaide Health Study (NWAHS). The cohort has so far participated in three stages of the MAILES Study: MAILES1 (FAMAS Wave 1, from 2002-2005, and NWAHS Wave 2, from 2004-2006); MAILES2 (FAMAS Wave 2, from 2007-2010, and NWAHS Wave 3, from 2008-2010); and MAILES3 (a computer-assisted telephone interview (CATI) survey of all participants in the study, conducted in 2010). Data have been collected on a comprehensive range of physical, psychosocial and demographic issues relating to a number of chronic conditions (including cardiovascular disease, diabetes, arthritis and mental health) and health-related risk factors (including obesity, blood pressure, smoking, diet, alcohol intake and inflammatory markers), as well as on current and past health status and medication.

Keywords: Men; chronic disease; cohort studies; longitudinal studies; risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Alcohol Drinking / epidemiology
  • Androgens / metabolism*
  • Australia / epidemiology
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / immunology
  • Cardiovascular Diseases / metabolism
  • Cohort Studies
  • Diabetes Mellitus / epidemiology*
  • Diabetes Mellitus / immunology
  • Diabetes Mellitus / metabolism
  • Environment*
  • Humans
  • Hypercholesterolemia / epidemiology
  • Hypercholesterolemia / immunology
  • Hypercholesterolemia / metabolism
  • Hypertension / epidemiology
  • Hypertension / immunology
  • Hypertension / metabolism
  • Inflammation / immunology*
  • Life Style*
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Obesity / epidemiology
  • Obesity / immunology
  • Obesity / metabolism
  • Risk Factors
  • Smoking / epidemiology
  • Stress, Psychological / epidemiology*
  • Stress, Psychological / immunology
  • Stress, Psychological / metabolism

Substances

  • Androgens