Abstract
We investigated the set of Escherichia coli isolates originating from newborns in relation to resistance, virulence factors (VFs), phylogenetic groups, plasmid replicon typing, and genotypes. The most isolates were clustered in ECOR group B2. Extended-spectrum beta-lactamase phenotype was found in 27.7% of isolates. The ST131 clone was detected among 33 strains, 12 of which carried the CTX-M-15 gene. Most VFs were detected among ST131 isolates and in the B2 group. IbeA gene was found more frequently in the blood isolates, while the iha gene, in the urine isolates. The 3 most prevalent replicon types were IncFIB, IncF, and IncFIA.
Keywords:
E. coli; Genotyping; Plasmid replicon typing; Resistance; Virulence.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Bacterial Typing Techniques
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Drug Resistance, Bacterial
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Escherichia coli / classification
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Escherichia coli / drug effects
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Escherichia coli / genetics*
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Escherichia coli / isolation & purification
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Escherichia coli Infections / drug therapy
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Escherichia coli Infections / epidemiology*
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Escherichia coli Infections / microbiology*
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Escherichia coli Proteins / genetics
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Escherichia coli Proteins / metabolism
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Humans
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Infant, Newborn
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Intensive Care Units, Neonatal
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Membrane Proteins / genetics
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Membrane Proteins / metabolism
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Microbial Sensitivity Tests
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Phylogeny
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Plasmids
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Poland / epidemiology
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Replicon
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Virulence Factors / genetics*
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Virulence Factors / metabolism
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beta-Lactamases / classification
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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CusC protein, E coli
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Escherichia coli Proteins
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Membrane Proteins
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Virulence Factors
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beta-Lactamases