Abstract
The role of vitamin D (25-OH-D, or 25-hydroxyvitamin D) and its potential confounders in relationship to melanoma risk and mortality is discussed. The paradox that ultraviolet radiation (UVR) exposure is the major environmental risk factor for melanoma etiology as well as a major source of vitamin D might be explained by viewing vitamin D levels as the result of a healthy lifestyle rather than a cause of health.
© 2012 John Wiley & Sons A/S.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Dietary Supplements
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Genetic Predisposition to Disease / epidemiology
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Humans
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Incidence
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Melanoma / blood
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Melanoma / drug therapy
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Melanoma / genetics
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Melanoma / mortality*
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Pigmentation / genetics
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Risk Factors
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Skin Neoplasms / blood
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Skin Neoplasms / drug therapy
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Skin Neoplasms / genetics
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Skin Neoplasms / mortality*
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Sunscreening Agents / therapeutic use
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Ultraviolet Rays
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Vitamin D / blood
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Vitamin D / metabolism*
Substances
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Sunscreening Agents
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Vitamin D