Current incidence and residual risk of HIV, HBV and HCV at Canadian Blood Services

Vox Sang. 2012 Jul;103(1):83-6. doi: 10.1111/j.1423-0410.2012.01584.x. Epub 2012 Jan 31.

Abstract

Estimates of the viral residual risk should be updated to reflect current incidence of infection in blood donors. Incidence rates were estimated for allogeneic whole-blood donations made to Canadian Blood Services from 2006 to 2009 based on transmissible disease conversions of repeat donations within a 3-year period. Residual risk was estimated as the incidence multiplied by the window period. The residual risk of HIV was 1 per 8 million donations, HCV 1 per 6·7 million donations and HBV 1 per 1·7 million donations. The residual risk remains low and has decreased for HCV since our previous estimates due to reduced incidence.

MeSH terms

  • Blood Donors / statistics & numerical data*
  • Blood Transfusion / statistics & numerical data*
  • Canada / epidemiology
  • HIV Infections / blood
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV-1 / isolation & purification
  • HIV-2 / isolation & purification
  • Hepacivirus / isolation & purification
  • Hepatitis B / blood
  • Hepatitis B / epidemiology*
  • Hepatitis B / transmission
  • Hepatitis B virus / isolation & purification
  • Hepatitis C / blood
  • Hepatitis C / epidemiology*
  • Hepatitis C / transmission
  • Humans
  • Incidence
  • Risk Factors
  • Transfusion Reaction