Stearidonic acid as a 'pro-eicosapentaenoic acid'

Curr Opin Lipidol. 2012 Feb;23(1):30-4. doi: 10.1097/MOL.0b013e32834f0f0c.

Abstract

Purpose of review: ω-3 Fatty acids continue to be promoted as cardioprotective, generating an increased demand for these nutrients. Ocean-based supplies are limited, and so land-based sources are being sought. Stearidonic acid-fortified soybean oil may help to meet this demand.

Recent findings: Stearidonic acid has been shown in animal and human studies to be more effective than its precursor, α-linolenic acid, in enriching membranes with eicosapentaenoic acid. Hence, stearidonic acid can serve as a 'pro-eicosapentaenoic acid'.

Summary: Stearidonic acid-fortified soybean oil may be able to help close the gap between actual and recommended intakes of ω-3 fatty acids in an environmentally friendly manner.

Publication types

  • Review

MeSH terms

  • Animals
  • Biotransformation
  • Cell Membrane / metabolism
  • Dietary Fats
  • Eicosapentaenoic Acid / metabolism*
  • Erythrocytes / metabolism
  • Fatty Acids, Omega-3 / metabolism*
  • Food, Fortified
  • Humans
  • Soybean Oil / metabolism

Substances

  • Dietary Fats
  • Fatty Acids, Omega-3
  • Soybean Oil
  • Eicosapentaenoic Acid
  • stearidonic acid