Effect of a telemonitoring-facilitated collaboration between general practitioner and heart failure clinic on mortality and rehospitalization rates in severe heart failure: the TEMA-HF 1 (TElemonitoring in the MAnagement of Heart Failure) study

Eur J Heart Fail. 2012 Mar;14(3):333-40. doi: 10.1093/eurjhf/hfr144. Epub 2011 Nov 1.

Abstract

Aims: Chronic heart failure (CHF) patients are frequently rehospitalized within 6 months after an episode of fluid retention. Rehospitalizations are preventable, but this requires an extensive organization of the healthcare system. In this study, we tested whether intensive follow-up of patients through a telemonitoring-facilitated collaboration between general practitioners (GPs) and a heart failure clinic could reduce mortality and rehospitalization rate.

Methods and results: One hunderd and sixty CHF patients [mean age 76 ± 10 years, 104 males, mean left ventricular ejection fraction (LVEF) 35 ± 15%] were block randomized by sealed envelopes and assigned to 6 months of intense follow-up facilitated by telemonitoring (TM) or usual care (UC). The TM group measured body weight, blood pressure, and heart rate on a daily basis with electronic devices that transferred the data automatically to an online database. Email alerts were sent to the GP and heart failure clinic to intervene when pre-defined limits were exceeded. All-cause mortality was significantly lower in the TM group as compared with the UC group (5% vs. 17.5%, P = 0.01). The total number of follow-up days lost to hospitalization, dialysis, or death was significantly lower in the TM group as compared with the UC group (13 vs. 30 days, P = 0.02). The number of hospitalizations for heart failure per patient showed a trend (0.24 vs. 0.42 hospitalizations/patient, P = 0.06) in favour of TM.

Conclusion: Telemonitoring-facilitated collaboration between GPs and a heart failure clinic reduces mortality and number of days lost to hospitalization, death, or dialysis in CHF patients. These findings need confirmation in a large trial.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Analysis of Variance
  • Antihypertensive Agents / therapeutic use
  • Cardiac Care Facilities / statistics & numerical data*
  • Cooperative Behavior
  • Female
  • General Practitioners / statistics & numerical data*
  • Heart Failure / drug therapy
  • Heart Failure / mortality*
  • Hospitalization / statistics & numerical data*
  • Humans
  • Male
  • Risk Factors
  • Severity of Illness Index
  • Stroke Volume
  • Telemedicine / instrumentation*
  • Telemedicine / methods
  • Treatment Failure
  • Ventricular Function, Left

Substances

  • Antihypertensive Agents

Associated data

  • ISRCTN/ISRCTN39223875