Infectious diarrhea is both a local and a global concern. Illnesses can range from mild inconveniences to life-threatening epidemics. Although diarrhea can be caused by a vast array of pathogens, the cornerstone of prevention is provision of a safe food and water supply, application of basic hygiene principles, and the development and administration of vaccines. The cornerstone of treatment is rehydration. Selection of specific antimicrobial therapy should be based on disease presentation and epidemiologic factors.
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