High prevalence of vitamin D deficiency in Zahedan, southeast Iran

Ann Nutr Metab. 2011;58(1):37-41. doi: 10.1159/000323749. Epub 2011 Feb 8.

Abstract

Background: Several studies show a high prevalence of vitamin D deficiency in Asia. Data regarding the prevalence of vitamin D deficiency in southeast Iran are inadequate.

Objectives: The purpose of this study was to determine the prevalence of vitamin D deficiency in Zahedan, a sunny area in southeast Iran.

Subjects and methods: This population-based cross-sectional study was performed on 993 apparently healthy subjects. Serum levels of 25-hydroxy vitamin D (25-OH vit D), parathyroid hormone, calcium, phosphate, and alkaline phosphatase activity were measured.

Results: Inadequate vitamin D status was diagnosed in 94.7% of the subjects (25-OH vit D <30 ng/ml). The frequencies of deficiency (<20 ng/ml), insufficiency (20-30 ng/ml), sufficiency (30-150 ng/ml), and toxicity (>150 ng/ml) were 85.2, 9.5, 5.3, and 0.0%, respectively.

Conclusion: The results indicate that vitamin D deficiency is common in the population of Zahedan. Based on our results, fortification of milk and the use of supplements is suggested in this region.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Alkaline Phosphatase / blood
  • Calcium, Dietary / blood
  • Cross-Sectional Studies
  • Female
  • Humans
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Parathyroid Hormone / blood
  • Phosphates / blood
  • Prevalence
  • Sunlight
  • Vitamin D / analogs & derivatives*
  • Vitamin D / blood
  • Vitamin D Deficiency / blood*
  • Vitamin D Deficiency / epidemiology*
  • Young Adult

Substances

  • Calcium, Dietary
  • Parathyroid Hormone
  • Phosphates
  • Vitamin D
  • 25-hydroxyvitamin D
  • Alkaline Phosphatase