Health-related quality of life in patients with multiple injuries and traumatic brain injury 10+ years postinjury

J Trauma. 2010 Sep;69(3):523-30; discussion 530-1. doi: 10.1097/TA.0b013e3181e90c24.

Abstract

Background: The aim of this study was to examine the long-term physical and psychological consequences of multiple blunt forced trauma at ≥ 10-year follow-up for patients with and without traumatic brain injury (TBI).

Methods: A total of 620 patients with multiple injuries were assessed with the Medical Outcomes Study-Short Form-12 and a physical reexamination at ≥ 10-year follow-up. Injury-related characteristics were collected from patients' medical record. Chi-square analysis, Analysis of Variance, and linear and logistic regression were performed to test differences between groups and examine predictors of physical and psychological functioning at ≥ 10-year follow-up.

Results: Patients with multiple injuries who sustained a TBI (n = 398) were more likely to be female (p = 0.001), younger in age at the time of injury (p = 0.02), have higher Injury Severity Scores (p = 0.001), shorter ward stays (p = 0.001), and a greater number of upper extremity injuries (p = 0.02) when compared with those without TBI (n = 222). Patients with TBI reported poorer psychological functioning (p = 0.02) and more frequently reported chronic pain (p = 0.01). Patients with TBI used medical aids (p = 0.002) less frequently at follow-up when compared with patients without TBI. Significant predictors of health-related quality of life at ≥ 10-year follow-up included age at the time of injury (physical; p = 0.001), gender (p = 0.05), number of ventilation days (p = 0.02), satisfaction with rehabilitation (p = 0.001), disability caused by the injury (p = 0.001), and use of medical aids (physical p = 0.02).

Conclusions: Prospective studies are needed with a broader range of measures that may be sensitive to the consequences of TBI. Evidence-based interventions to facilitate physical and psychological rehabilitation, designed to target at risk patients, are warranted.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Adolescent
  • Adult
  • Analysis of Variance
  • Brain Injuries / complications*
  • Brain Injuries / psychology
  • Brain Injuries / rehabilitation
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Humans
  • Injury Severity Score
  • Length of Stay
  • Linear Models
  • Logistic Models
  • Male
  • Middle Aged
  • Multiple Trauma / complications*
  • Multiple Trauma / psychology
  • Multiple Trauma / rehabilitation
  • Pain / etiology
  • Quality of Life*
  • Time Factors
  • Young Adult