Fatigue and its correlates in cancer patients who had returned to work--a cohort study

Psychooncology. 2011 Nov;20(11):1236-41. doi: 10.1002/pon.1843. Epub 2010 Sep 5.

Abstract

Objectives: Fatigue and other symptoms in cancer patients often interfere with social and occupational activities. Only a few studies, however, have examined relationship between fatigue and work-related outcomes. The aim of this study was to investigate which disease-related factors (treatment, diagnosis, cognitive dysfunction, depression, pain, and sleep disturbance) and work-related factors (work-load, work pressure, relationship to supervisor and colleagues, size of the company, and workplace accommodations) were related to fatigue in employed cancer survivors.

Methods: Data was collected by questionnaire at 6 months (baseline) and 18 months (end of the follow-up) after cancer diagnosis from 135 people with different types of cancer who had returned to work at follow-up. Fatigue was measured with a four-item sub-scale of MFI. Scores ranged from 4 to 20, with higher scores indicating more fatigue.

Results: The mean rate of general fatigue was 11.9 at baseline decreasing to 10.4 at the end of the follow-up (p<0.0001). At 6 months, higher work pressure (p = 0.02), physical workload (p<0.05) and less workplace accommodations (p = 0.03) were related to higher levels of fatigue. From disease-related factors, depression was associated with fatigue (p<0.0001) at baseline. Lack of workplace accommodations was the only factor affecting higher levels of fatigue at 18 months (p<0.001) and was also related to higher levels of depression at 6 months (p = 0.02) and at 18 months (p<0.001).

Conclusions: Lack of workplace accommodations was significantly related to fatigue at the end of the follow-up, which suggests that accommodations for illness can help to reduce fatigue and depression.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Analysis of Variance
  • Chi-Square Distribution
  • Cohort Studies
  • Depression / etiology
  • Depression / psychology
  • Employment / psychology*
  • Fatigue / etiology*
  • Fatigue / psychology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasms / psychology*
  • Psychiatric Status Rating Scales
  • Sleep Wake Disorders / etiology
  • Sleep Wake Disorders / psychology
  • Surveys and Questionnaires
  • Time Factors
  • Young Adult