Personal genome research : what should the participant be told?

Amy L McGuire; James R Lupski

doi:10.1016/j.tig.2009.12.007

Personal genome research : what should the participant be told?

Trends Genet. 2010 May;26(5):199-201. doi: 10.1016/j.tig.2009.12.007. Epub 2010 Apr 8.

Authors

Amy L McGuire¹, James R Lupski

Affiliation

¹ Center for Medical Ethics and Health Policy, Baylor College of Medicine, One Baylor Plaza, BCM420 Houston, Texas 77030, USA. amcguire@bcm.edu

Abstract

Should the results of whole genome sequencing research be disclosed to participants, in particular when the results have uncertain or indeterminate phenotypic consequences? This controversial question is considered in light of one author's (J.L.) experience as a geneticist who recently had his own genome sequenced.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Data Interpretation, Statistical
Genetic Variation
Genome, Human*
Humans
Sequence Analysis, DNA / economics
Sequence Analysis, DNA / ethics*
Truth Disclosure / ethics*

Abstract

Publication types

MeSH terms

Grants and funding