Atopy patch test for early diagnosis of cow's milk allergy in preterm infants

J Pediatr Gastroenterol Nutr. 2010 Apr;50(4):463-4. doi: 10.1097/MPG.0b013e3181b97bed.

Abstract

Atopy patch test may help early diagnosis of cow-milk allergy in preterm infants. In the retrospective analysis of 5 girls and 9 boys, born at 31 +/- 2 (mean +/- SD) weeks of gestation and presenting digestive symptoms at age 42 +/- 18 days, 10 had a complete recovery following the shift to an exclusive feeding with an amino acid-based formula. Cow-milk-skin prick tests and specific immunoglobulin E were always negative, whereas the atopy patch test was positive in 7 of the 10 infants with complete recovery.

Publication types

  • Evaluation Study

MeSH terms

  • Amino Acids
  • Dietary Proteins / adverse effects*
  • Female
  • Humans
  • Hypersensitivity, Immediate / diagnosis*
  • Immunoglobulin E
  • Infant
  • Infant Formula*
  • Infant, Newborn / immunology*
  • Infant, Premature / immunology
  • Infant, Premature, Diseases / diagnosis*
  • Infant, Premature, Diseases / therapy
  • Male
  • Milk Hypersensitivity / diagnosis*
  • Milk Hypersensitivity / diet therapy
  • Patch Tests*
  • Retrospective Studies

Substances

  • Amino Acids
  • Dietary Proteins
  • Immunoglobulin E