Background: Patent blue is a commonly used agent in the detection of sentinel nodes (SN) in solid cancer. Similar to any drug, it is possible to have an allergic reaction during surgery. Anaphylactic reactions to patent blue have been rarely reported especially in cervical cancer.
Case: We reported here a rare case of anaphylactic shock due to patent blue in response to injection of patent blue for SN mapping in a woman with cervical cancer. We presented our management of the shock, our diagnostic process of the allergen and the treatment of the cervix cancer after the anaphylactic reaction.
Conclusion: Surgeons and anesthetists must be aware of the potential allergic of patent blue during the SN procedure.