Abstract
We report on 14 patients treated with linac- or robotic image-guided stereotactic radiotherapy for isolated lymph node recurrence from prostate cancer, up to the mean dose of 30Gy/3 fractions. At the mean follow-up of 18.6months, five patients experienced clinical out-field progression. Toxicity was minimal. Further investigation is warranted in order to identify the patients that benefit most from this treatment modality and to define the optimal association of such local approach with androgen deprivation. Hopefully, effective local therapy might reduce the burden of systemic therapies given to the recurrent/metastatic prostate cancer patients.
MeSH terms
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Aged
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Cohort Studies
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Dose-Response Relationship, Radiation
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Follow-Up Studies
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Humans
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Lymph Nodes / pathology
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Lymph Nodes / radiation effects*
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Lymphatic Metastasis
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Male
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Middle Aged
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Neoplasm Recurrence, Local / mortality
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Neoplasm Recurrence, Local / pathology
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Neoplasm Recurrence, Local / radiotherapy*
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Prostatic Neoplasms / mortality
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Prostatic Neoplasms / pathology
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Prostatic Neoplasms / radiotherapy*
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Radiosurgery / instrumentation*
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Radiosurgery / methods
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Radiotherapy Dosage
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Radiotherapy Planning, Computer-Assisted / instrumentation
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Radiotherapy Planning, Computer-Assisted / methods*
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Radiotherapy, Intensity-Modulated / instrumentation
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Radiotherapy, Intensity-Modulated / methods
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Retrospective Studies
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Risk Assessment
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Robotics / methods*
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Survival Analysis
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Treatment Outcome