Abstract
Conflicting conclusions present in earlier studies on the relationship between sperm chromatin anomalies and outcome of conventional in vitro fertilization (IVF) may result from confounding by poorly controlled external factors. We examined the relationship of sperm chromatin parameters and outcome of conventional IVF while strictly controlling external factors.
MeSH terms
-
Adult
-
Chromatin / chemistry
-
Chromatin / metabolism*
-
Confounding Factors, Epidemiologic
-
DNA Damage / physiology*
-
Female
-
Fertilization in Vitro* / methods
-
Fertilization in Vitro* / statistics & numerical data
-
Humans
-
Infertility, Male / epidemiology*
-
Infertility, Male / genetics
-
Infertility, Male / therapy*
-
Male
-
Pregnancy
-
Pregnancy Rate
-
Risk Factors
-
Semen Analysis / methods
-
Spermatozoa / metabolism*
-
Treatment Outcome