Dietary protein recommendations and the prevention of sarcopenia

Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):86-90. doi: 10.1097/MCO.0b013e32831cef8b.

Abstract

Purpose of review: To draw attention to recent work on the role of protein and the amount of protein needed with each meal to preserve skeletal muscle mass in ageing.

Recent findings: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individuals. However, muscle protein synthesis is blunted in elderly when protein and carbohydrate are coingested or when the quantity of protein is less than approximately 20 g per meal. Supplementing regular mixed-nutrient meals with leucine may also enhance the muscle protein synthetic response in elders.

Summary: On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30 g of high quality protein per meal.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aged
  • Aging / physiology*
  • Dietary Proteins / administration & dosage
  • Dietary Proteins / therapeutic use*
  • Dietary Supplements
  • Exercise / physiology
  • Humans
  • Leucine / therapeutic use
  • Muscle Proteins / biosynthesis
  • Muscular Atrophy / metabolism
  • Muscular Atrophy / prevention & control*
  • Nutrition Policy
  • Protein Deficiency / metabolism
  • Protein Deficiency / prevention & control*

Substances

  • Dietary Proteins
  • Muscle Proteins
  • Leucine