Abstract
We report a case of naturally acquired Plasmodium knowlesi in Singapore, a malaria-free country. Diagnosis was confirmed by PCR with validated species-specific primers. In industrialized countries, free-ranging primates are a potential source of P. knowlesi human infection. P. knowlesi infection is a differential diagnosis of febrile illness acquired in Singapore.
MeSH terms
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Adult
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Animals
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DNA Primers
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DNA, Protozoan / analysis
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Diagnosis, Differential
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Fever / diagnosis
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Humans
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Macaca / parasitology
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Malaria / diagnosis*
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Malaria / parasitology
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Malaria / transmission*
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Male
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Monkey Diseases / parasitology
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Monkey Diseases / transmission*
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Plasmodium knowlesi / classification
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Plasmodium knowlesi / genetics
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Plasmodium knowlesi / isolation & purification*
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Polymerase Chain Reaction / methods
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Singapore / epidemiology
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Species Specificity
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Zoonoses / parasitology
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Zoonoses / transmission*
Substances
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DNA Primers
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DNA, Protozoan