Case-control study on occupational risk factors for soft-tissue sarcoma

J Occup Environ Med. 2007 Dec;49(12):1386-93. doi: 10.1097/JOM.0b013e318157d2f2.

Abstract

Objective: The main objective of this study was to investigate potential association between development of soft-tissue sarcoma (STS) and occupational exposures related to farming and the agricultural industry in Canada.

Methodology: A population-based case-control study of STS was conducted among Canadian men stratified by province of residence and age group. Conditional logistic regression was used to fit multivariable statistical models.

Results: The following variables were positively associated with the incidence of STS: machinist, chicken farming, pulp and paper industry worker, and apartment complex worker. Mixed farming and exposure to chlorine were negatively associated with STS.

Conclusion: The higher risk of developing STS may be associated with longest-held job as a machinist, short-term jobs as chicken farm worker, pulp and paper industry worker, and apartment complex worker.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Agriculture*
  • Canada
  • Case-Control Studies
  • Cross-Sectional Studies
  • Employment / statistics & numerical data
  • Health Surveys
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Occupational Diseases / epidemiology*
  • Occupational Exposure / adverse effects
  • Occupational Exposure / statistics & numerical data*
  • Risk Factors
  • Sarcoma / epidemiology*