Aging-related sleep changes

Clin Geriatr Med. 2008 Feb;24(1):1-14, v. doi: 10.1016/j.cger.2007.08.007.

Abstract

Normal aging is accompanied by changes in the sleep quality, quantity, and architecture. Specifically, there appears to be a measurable decrease in the ability of the healthy elderly to initiate and maintain sleep, accompanied by a decrease in the proportion of the deeper, more restorative slow-wave sleep and rapid eye movement sleep. There is epidemiologic evidence that this impaired ability to initiate, maintain, and ultimately achieve good quality, optimal sleep may be a marker of increased mortality and neurocognitive dysfunction. Possible mechanisms related to these age-related changes in sleep include age-related changes in circadian modulation, homeostatic factors, cardiopulmonary function, and endocrine function. This article describes the normal changes in sleep physiology in the elderly.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Circadian Rhythm / physiology
  • Cognition / physiology
  • Growth Hormone / blood
  • Humans
  • Hydrocortisone / blood
  • Polysomnography
  • Respiration
  • Sleep / physiology*
  • Sleep Deprivation / physiopathology
  • Sleep Initiation and Maintenance Disorders / epidemiology
  • Sleep Initiation and Maintenance Disorders / physiopathology
  • Sleep Wake Disorders / epidemiology*
  • Sleep Wake Disorders / physiopathology*
  • Sleep, REM / physiology
  • Time Factors

Substances

  • Growth Hormone
  • Hydrocortisone