[Management of severe pre-eclampsia in the puerperium. Comparative study of sublingual nifedipine and hydralazine]

Ginecol Obstet Mex. 1991 Jul:59:207-10.
[Article in Spanish]

Abstract

At random, two therapeutic schemes for severe preeclampsia during the puerperium, were evaluated. Group A (n = 20) was left without antihypertensive medication and sublingual nifedipine was used only in case of diastolic pressure of 110 mmHg or more. Group B (n = 18) receive Hydralazine 40 mlg. per os, every 6 hrs.; in this group also, nifedipine was administered in case of diastolic pressure of 110 mmHg or more. The only differences were that in group B the intervals for the administration of nifedipine were much shorter than in group A; also, in the same group the need for another antihypertensive was more frequent (5 of 18 vs 1 of 20 patients).

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Administration, Sublingual
  • Adolescent
  • Adult
  • Antihypertensive Agents / administration & dosage
  • Antihypertensive Agents / therapeutic use
  • Female
  • Humans
  • Hydralazine / therapeutic use*
  • Nifedipine / administration & dosage
  • Nifedipine / therapeutic use*
  • Pre-Eclampsia / drug therapy*
  • Pregnancy
  • Puerperal Disorders / drug therapy*

Substances

  • Antihypertensive Agents
  • Hydralazine
  • Nifedipine