Malnutrition among gynaecological cancer patients

Eur J Clin Nutr. 2007 May;61(5):642-6. doi: 10.1038/sj.ejcn.1602540. Epub 2006 Oct 4.

Abstract

Objective: To assess the nutritional status of patients with gynaecological cancer.

Design: A prospective study assessing the nutritional status of gynaecological patients with suspected or proven gynaecological cancer.

Setting: Queensland Centre for Gynaecological Cancer, Brisbane, Australia; a tertiary referral centre for gynaecological cancer.

Subjects: One hundred forty-five patients with suspected or proven gynaecological cancer aged 20-91 years.

Intervention: Scored patient-generated subjective global assessment (PG-SGA) and serum albumin before treatment.

Results: One hundred and sixteen (80%) patients were categorized as PG-SGA class A, 29 (20%) patients were PG-SGA B and none of the patients were PG-SGA C. Ovarian cancer patients had significantly lower serum albumin levels (P=0.003) and higher PG-SGA scores (P<0.001) than patients with other types of cancer and benign conditions. Sixty-seven per cent of patients with ovarian cancer were classified as PG-SGA B. After adjusting for patient's age, body mass index and albumin level, ovarian cancer patients were 19 times more likely to be categorized as PG-SGA class B compared to patients with benign conditions (95% confidence interval: 3.03-129.8; P=0.002).

Conclusion: Malnutrition in gynaecological cancer patients is a significant problem, especially among those patients diagnosed with ovarian cancer.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Comorbidity
  • Female
  • Genital Neoplasms, Female / complications
  • Genital Neoplasms, Female / epidemiology*
  • Genital Neoplasms, Female / pathology
  • Humans
  • Malnutrition / epidemiology*
  • Middle Aged
  • Nutrition Assessment*
  • Nutritional Status*
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / epidemiology*
  • Ovarian Neoplasms / pathology
  • Prospective Studies
  • Queensland / epidemiology
  • Serum Albumin / analysis*
  • Severity of Illness Index

Substances

  • Serum Albumin