Predisposition of antituberculosis drug induced hepatotoxicity by cytochrome P450 2E1 genotype and haplotype in pediatric patients

J Gastroenterol Hepatol. 2006 Apr;21(4):784-6. doi: 10.1111/j.1440-1746.2006.04197.x.

Authors

Bidyut Roy, Sanat Kumar Ghosh, Debabrata Sutradhar, Nilabja Sikdar, Santasree Mazumder, Santanu Barman

PMID: 16677176
DOI: 10.1111/j.1440-1746.2006.04197.x

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antitubercular Agents*
Chemical and Drug Induced Liver Injury / enzymology
Chemical and Drug Induced Liver Injury / epidemiology*
Chemical and Drug Induced Liver Injury / genetics*
Cytochrome P-450 Enzyme System / genetics*
DNA Mutational Analysis / methods
Female
Genetic Predisposition to Disease / epidemiology
Genetic Predisposition to Disease / genetics
Genetic Testing / methods*
Genotype
Haplotypes
Humans
Incidence
India / epidemiology
Male
Middle Aged
Polymorphism, Genetic
Risk Assessment / methods*
Risk Factors

Substances

Antitubercular Agents
Cytochrome P-450 Enzyme System