Pathogenesis of liver involvement during dengue viral infections

Trans R Soc Trop Med Hyg. 2006 Jul;100(7):608-14. doi: 10.1016/j.trstmh.2005.10.007. Epub 2006 Feb 17.

Abstract

The dengue virus can infect many cell types and cause diverse clinical and pathological effects. We describe clinical and experimental observations that suggest that liver involvement occurs during dengue infections, and we outline the possible role played by host immune responses in this process.

Publication types

  • Review

MeSH terms

  • Alanine Transaminase / analysis
  • Apoptosis / immunology
  • Aspartate Aminotransferases / analysis
  • B-Lymphocytes / immunology
  • Dengue / enzymology
  • Dengue / immunology
  • Dengue / virology*
  • Dengue Virus / metabolism
  • Hepatomegaly / virology
  • Humans
  • Immunity / immunology
  • Liver / enzymology
  • Liver / immunology
  • Liver / virology*
  • Liver Diseases / enzymology
  • Liver Diseases / immunology
  • Liver Diseases / virology*
  • T-Lymphocytes / immunology

Substances

  • Aspartate Aminotransferases
  • Alanine Transaminase