Abstract
Treatment of gestational multidrug-resistant tuberculosis (MDR-TB) is controversial. We describe follow-up of 6 children exposed to second-line antituberculous agents in utero. Each child (average age, 3.7 years) underwent comprehensive clinical evaluation. One child had MDR-TB diagnosed. There was no evidence of significant late-presentation toxicity among the children. The results suggest that aggressive management of gestational MDR-TB may benefit both mother and child.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antitubercular Agents / adverse effects*
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Antitubercular Agents / therapeutic use*
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Child
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Child, Preschool
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Drug Resistance, Multiple, Bacterial
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Drug Therapy, Combination
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Female
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Follow-Up Studies
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Humans
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Infant
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Infectious Disease Transmission, Vertical / prevention & control
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Male
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Mycobacterium tuberculosis / drug effects
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Pregnancy
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Pregnancy Complications, Infectious / drug therapy*
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Prenatal Exposure Delayed Effects / chemically induced*
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Time Factors
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Tuberculosis / drug therapy*