Initial experience using magnetic resonance imaging in prenatal diagnosis of osteogenesis imperfecta type II: a case report

Clin Imaging. 2003 Jan-Feb;27(1):55-8. doi: 10.1016/s0899-7071(02)00480-1.

Abstract

We report a fetus with osteogenesis imperfecta (OI) first diagnosed by ultrasound in routine prenatal examination and further evaluated by magnetic resonance imaging (MRI). Fetal MRI was undertaken with a 1.5-T magnet using a body-phased array coil and an ultrafast imaging technique, half-Fourier single-shot turbo spin-echo (HASTE). Radiological examination shortly after birth and postmortem examination confirmed the prenatal diagnosis. In this case, fetal MRI provided excellent spatial and tissue resolution with multiplanar display. It revealed additional diagnostic information and improved imaging conspicuity. MRI complemented sonography for further differentiating clinical and sonographic findings.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Apgar Score
  • Cesarean Section
  • Fatal Outcome
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging / methods*
  • Osteogenesis Imperfecta / diagnosis*
  • Osteogenesis Imperfecta / embryology
  • Pregnancy
  • Pregnancy Outcome
  • Prenatal Diagnosis / methods
  • Respiratory Distress Syndrome, Newborn / diagnosis
  • Sensitivity and Specificity
  • Ultrasonography, Prenatal / methods*