Chest
Volume 126, Issue 4, Supplement, October 2004, Page 889S
Poster PresentationsInhibition of Bleomycin-Induced Pulmonary Fibrosis by Okam Extract J201
Section snippets
Abstract
PURPOSE: To explore the inhibitory effect of okam extract J201 on bleomycin-induced pulmonary fibrosis and its underlying mechanism of action.
METHODS: Inhibition of proliferation and collagen synthesis of human lung fibroblast by okam extract J201 and its effect on PDGF were measured by MTT assay and Sircol Soluble Collagen Assay in vitro. Using bleomycin-induced pulmonary fibrosis animal model, its effects on mouse lung index, concentration of serum IL-4, INF-r were measured with ELISA. The
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Copyright © 2004 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.