Environmental and Occupational DisordersEffect of mattress and pillow encasings on children with asthma and house dust mite allergy☆,☆☆
Section snippets
Population
A total of 60 children (age range, 5-15 years) with asthma and documented allergy to HDMs from the Departments of Pediatrics at Sønderborg, Kolding, and Viborg Hospitals, Denmark, were included.
The inclusion criteria were all of the following: doctor-diagnosed asthma; a positive skin prick test (SPT) response to HDM (Dermatophagoides pteronyssinus) ; a positive bronchial provocation test result with HDM allergen extract (D pteronyssinus ; PC20 less than 100,000 SQU); and a total HDM
Results
A total of 60 patients were included and randomized, and as seen in Fig 2, data from 47 children, 26 actively treated patients and 21 control subjects, were included in the final analysis.
A total of 4 children in the
Discussion
HDM allergy is the most common cause of allergic asthma in childhood. The relationship between exposure and asthma symptoms in sensitized individuals is complex, with some patients reacting to very low doses of allergen, whereas other patients tolerate rather high doses.4, 19 Meanwhile, exposure to higher allergen levels usually is associated with more severe asthma in sensitized patients. Avoidance of HDM allergen exposure seems to be the most logical way to treat children with asthma and HDM
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Cited by (150)
GEMA 5.3. Spanish Guideline on the Management of Asthma
2023, Open Respiratory ArchivesAsthma Management in Children
2023, Journal of Allergy and Clinical Immunology: In Practice2020 Updated Asthma Guidelines: Indoor allergen reduction
2020, Journal of Allergy and Clinical Immunology2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group
2020, Journal of Allergy and Clinical ImmunologyCitation Excerpt :The evidence was insufficient to allow the Expert Panel to examine the use of cleaning products.97 In contrast, dust mite mitigation using impermeable mattress and pillow covers as a single intervention was the subject of many RCTs, which yielded moderate certainty of evidence of no benefit for the critical outcomes, including asthma symptoms.98-109 Results for pet removal were inconclusive.110
Risk prediction of household mite infestation based on machine learning
2020, Building and EnvironmentCitation Excerpt :Nature ventilation can affect the HDM allergen concentrations by reducing indoor humidity only in the dry regions [22–25]. In terms of mite prevention, occupant behavior, including reducing indoor humidity, increasing the frequency of cleaning (both wash cleaning and vacuum cleaning), and avoiding the use of excessive cotton fabrics have all been proven to be effective mite avoidance measures [26–28]. Despite the severe health effect of HDM allergens, people still pay little attention to prevent HDM allergens.
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Supported by the Danish Asthma and Allergy Association and the Danish Research Foundation.
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Reprint requests: Susanne Halken, MD, Department of Pediatrics, Sønderborg Hospital, DK-6400 Sønderborg, Denmark.