Semin Neurol 2009; 29(5): 534-540
DOI: 10.1055/s-0029-1241037
© Thieme Medical Publishers

Inner Ear Dysfunction Due to Vertebrobasilar Ischemic Stroke

Ji Soo Kim1 , Hyung Lee2
  • 1Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea
  • 2Department of Neurology, Brain Research Institute, Keimyung University School of Medicine, Daegu, South Korea
Further Information

Publication History

Publication Date:
15 October 2009 (online)

ABSTRACT

Because the blood supply to the inner ear originates from the vertebrobasilar system, vertebrobasilar ischemic stroke can present with vertigo and hearing loss due to infarction of the inner ear (i.e., labyrinthine infarction). Sometimes vertigo and hearing loss are warning symptoms of impending vertebrobasilar ischemic stroke (mainly in the anterior inferior cerebellar artery territory). In this case, the magnetic resonance imaging (MRI) scan is normal and the clinician must rely on other clinical features to make the diagnosis. Here the authors review the keys to the diagnosis of vertigo and hearing loss associated with vertebrobasilar ischemic stroke.

REFERENCES

  • 1 Mazzoni A. Internal auditory canal arterial relations at the porus acusticus.  Ann Otol Rhinol Laryngol. 1969;  78(4) 797-814
  • 2 Axellson A. The vascular anatomy of the cochlea in the guinea pig and man.  Acta Otolaryngol. 1968;  Suppl 243 1-134
  • 3 Mazzoni A. The vascular anatomy of the vestibular labyrinth in man.  Acta Otolaryngol Suppl. 1990;  472 1-83
  • 4 Perlman H B, Kimura R S, Fernandez C. Experiments on temporary obstruction of the internal auditory artery.  Laryngoscope. 1959;  69(6) 591-613
  • 5 Grad A, Baloh R W. Vertigo of vascular origin. Clinical and electronystagmographic features in 84 cases.  Arch Neurol. 1989;  46(3) 281-284
  • 6 Oas J G, Baloh R W. Vertigo and the anterior inferior cerebellar artery syndrome.  Neurology. 1992;  42(12) 2274-2279
  • 7 Mazzoni A. Internal auditory artery supply to the petrous bone.  Ann Otol Rhinol Laryngol. 1972;  81(1) 13-21
  • 8 Lee H, Cho Y W. Auditory disturbance as a prodrome of anterior inferior cerebellar artery infarction.  J Neurol Neurosurg Psychiatry. 2003;  74(12) 1644-1648
  • 9 Yi H A, Lee S R, Lee H, Ahn B H, Park B R, Whitman G T. Sudden deafness as a sign of stroke with normal diffusion-weighted brain MRI.  Acta Otolaryngol. 2005;  125(10) 1119-1121
  • 10 Lee H, Kim H J, Koo J W, Kim J S. Progression of acute cochleovestibulopathy into anterior inferior cerebellar artery infarction.  J Neurol Sci. 2009;  278(1-2) 119-122
  • 11 Kim J S, Cho K H, Lee H. Isolated labyrinthine infarction as a harbinger of anterior inferior cerebellar artery territory infarction with normal diffusion-weighted brain MRI.  J Neurol Sci. 2009;  278(1-2) 82-84
  • 12 Levine R A, Bu-Saba N, Brown M C. Laser-Doppler measurements and electrocochleography during ischemia of the guinea pig cochlea: implications for hearing preservation in acoustic neuroma surgery.  Ann Otol Rhinol Laryngol. 1993;  102(2) 127-136
  • 13 Lee H, Yi H A, Baloh R W. Sudden bilateral simultaneous deafness with vertigo as a sole manifestation of vertebrobasilar insufficiency.  J Neurol Neurosurg Psychiatry. 2003;  74(4) 539-541
  • 14 Schuknecht H F. Pathology of the Ear. 2nd ed. Philadelphia, PA; Lea and Febiger 1993
  • 15 Fife T D, Baloh R W, Duckwiler G R. Isolated dizziness in vertebrobasilar insufficiency: clinical features, angiography, and follow-up.  J Stroke Cerebrovasc Dis. 1994;  4 4-12
  • 16 Gomez C R, Cruz-Flores S, Malkoff M D, Sauer C M, Burch C M. Isolated vertigo as a manifestation of vertebrobasilar ischemia.  Neurology. 1996;  47(1) 94-97
  • 17 Choi K D, Shin H Y, Kim J S et al.. Rotational vertebral artery syndrome: oculographic analysis of nystagmus.  Neurology. 2005;  65(8) 1287-1290
  • 18 Kim J S, Lopez I, DiPatre P L, Liu F, Ishiyama A, Baloh R W. Internal auditory artery infarction: clinicopathologic correlation.  Neurology. 1999;  52(1) 40-44
  • 19 Hemenway W G, Lindsay J R. Postural vertigo due to unilateral sudden partial loss of vestibular function.  Ann Otol Rhinol Laryngol. 1956;  65 692-706
  • 20 Inui H, Murai T, Yane K, Matsunaga T. Brainstem ischemic damage following occlusion of the blood vessels in the rat's posterior cerebral circulation.  Eur Arch Otorhinolaryngol. 1996;  253(3) 176-181
  • 21 Amarenco P, Hauw J J. Cerebellar infarction in the territory of the anterior and inferior cerebellar artery. A clinicopathological study of 20 cases.  Brain. 1990;  113(Pt 1) 139-155
  • 22 Amarenco P, Rosengart A, DeWitt L D, Pessin M S, Caplan L R. Anterior inferior cerebellar artery territory infarcts. Mechanisms and clinical features.  Arch Neurol. 1993;  50(2) 154-161
  • 23 Hinojosa R, Kohut R I. Clinical diagnosis of anterior inferior cerebellar artery thrombosis. Autopsy and temporal bone histopathologic study.  Ann Otol Rhinol Laryngol. 1990;  99(4 Pt 1) 261-272
  • 24 Lee H, Lopez I, Ishiyama A, Baloh R W. Can migraine damage the inner ear?.  Arch Neurol. 2000;  57(11) 1631-1634
  • 25 Lee H, Sohn S I, Jung D K et al.. Sudden deafness and anterior inferior cerebellar artery infarction.  Stroke. 2002;  33(12) 2807-2812
  • 26 Lee H, Ahn B H, Baloh R W. Sudden deafness with vertigo as a sole manifestation of anterior inferior cerebellar artery infarction.  J Neurol Sci. 2004;  222(1-2) 105-107
  • 27 Rajesh R, Rafeequ M, Girija A S. Anterior inferior cerebellar artery infarct with unilateral deafness.  J Assoc Physicians India. 2004;  52 333-334
  • 28 Patzak M J, Demuth K, Kehl R, Lindner A. Sudden hearing loss as the leading symptom of an infarction of the left anterior inferior cerebellar artery.  HNO. 2005;  53(9) 797-799
  • 29 Son E J, Bang J H, Kang J G. Anterior inferior cerebellar artery infarction presenting with sudden hearing loss and vertigo.  Laryngoscope. 2007;  117(3) 556-558
  • 30 Lee H, Baloh R W. Sudden deafness in vertebrobasilar ischemia: clinical features, vascular topographical patterns, and long-term outcome.  J Neurol Sci. 2005;  228 99-104
  • 31 Lee H, Whitman G T, Lim J G, Lee S D, Park Y C. Bilateral sudden deafness as a prodrome of anterior inferior cerebellar artery infarction.  Arch Neurol. 2001;  58(8) 1287-1289
  • 32 Deschauer M, Georgiadis D, Lindner A. Hearing loss as the leading symptom in anterior inferior cerebellar artery infarction.  Fortschr Neurol Psychiatr. 1998;  66(3) 109-112
  • 33 Kim H A, Lee S R, Lee H. Acute peripheral vestibular syndrome of a vascular cause.  J Neurol Sci. 2007;  254(1-2) 99-101
  • 34 Dieterich M, Brandt T. Ocular torsion and tilt of subjective visual vertical are sensitive brainstem signs.  Ann Neurol. 1993;  33(3) 292-299
  • 35 Lee H, Lee S Y, Lee S R, Park B R, Baloh R W. Ocular tilt reaction and anterior inferior cerebellar artery syndrome.  J Neurol Neurosurg Psychiatry. 2005;  76(12) 1742-1743
  • 36 Lee H, Yi H A, Lee S R, Lee S Y, Park B R. Ocular torsion associated with infarction in the territory of the anterior inferior cerebellar artery: frequency, pattern, and a major determinant.  J Neurol Sci. 2008;  269(1-2) 18-23

Hyung LeeM.D. Ph.D. 

Department of Neurology, Keimyung University School of Medicine

194 Dongsan dong, Daegu, 700-712 South Korea

Email: hlee@dsmc.or.kr

    >