Original articleStroke Volume Variation as a Predictor of Fluid Responsiveness in Patients Undergoing One-Lung Ventilation
Section snippets
Methods
This study was approved by the Clinical Research Ethics Committee of the authors' hospital, and written informed consent was obtained from all patients before surgery. The patients were classified as American Society of Anesthesiologists risk I or II and scheduled for a pulmonary lobectomy under thoracoscopy requiring OLV for at least 1 hour with combined epidural/general anesthesia from April to July 2009. Exclusion criteria were risk of hepatic/renal/cardiac dysfunction and severe obesity
Results
A total of 30 patients were included in the study. All lobectomies were performed under thoracoscopy in the same way, and 18 patients (60%) had right-sided operations. There were no cases with massive blood loss (>50 mL) or requiring the administration of vasoactive agents during volume loading. Table 1 shows data representing the hemodynamic variables at time points T1 and T2. Except for HR, all hemodynamic variables changed significantly (p < 0.05) after volume loading (between T1 and T2).
Discussion
Several studies have reported that systolic pressure variation and pulse pressure variation are valuable indicators of fluid responsiveness during mechanical ventilation, whereas CVP and PCWP have been found to be of little help for that prediction.14, 15, 16, 17, 18 However, the major limitations of most current dynamic indicators are their inability to be automatically and continuously monitored.19
The Vigileo-FloTrac system allows for automatic and continuous monitoring of SVV, which is
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