Research ArticleIn situ measurement of miR-205 in malignant melanoma tissue supports its role as a tumor suppressor microRNA
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Keywords
AQUA
melanoma
microRNA
mir-205
miRNA in situ hybridization
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Quantitative assessment of miRNAs in situ will allow rapid, accurate measurement of miRNAs in large cohorts of patients sampled in tissue microarrays. This approach is used successfully to assess the prognostic value of tumor suppressor miR-205 in melanoma and suggests potential for the use of miRNAs in future prognostic or predictive models.
© 2012 United States & Canadian Academy of Pathology.