Elsevier

Vision Research

Volume 44, Issue 24, November 2004, Pages 2793-2797
Vision Research

Retinal nerve fiber layer thinning in Parkinson disease

https://doi.org/10.1016/j.visres.2004.06.009Get rights and content
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Abstract

Retinal dopamine loss in Parkinson disease (PD) is reflected by visual neurophysiological dysfunction. We measured the thickness of the circumpapillary retinal nerve fiber layer (RNFL) in PD patients using optical coherence tomography. The thickness in the inferior quadrant of PD patients (147 ± 20 microns) was significantly thinner than that of controls (173 ± 12 microns; p = 0.002), while the inferotemporal area was the thinnest (146 ± 24 vs. 191 ± 21 microns; p = 0.0003). The results show significant loss of RNFL thickness in PD at specific sites.

Keywords

Parkinson
Retina
Retinal nerve fiber layer
Optical coherence tomography

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