Coronary Artery DiseaseAssociation of Platelet-to-Lymphocyte Ratio With Severity and Complexity of Coronary Artery Disease in Patients With Acute Coronary Syndromes
Section snippets
Methods
From July 2012 to March 2014, consecutive patients who were hospitalized at our institution because of ACS, who underwent urgent CA after diagnosis, were enrolled in our study.
Initially 1,049 patients were admitted for analysis. Thirty-three patients were excluded from the study for the following reasons: 6 patients were excluded because of unavailability of laboratory data, 2 patients had histories of malignancy, 18 patients had histories of coronary artery bypass grafting, 5 patients had
Results
A total of 1,016 patients with ACS who underwent urgent CA were enrolled in the study. The mean age was 61.4 ± 12.9 years, and 286 of the patients (28.1%) were women. While 678 patients (66.7%) had low SXscores (≤22), 338 patients (33.3%) had intermediate to high SXscores (≥23).
Differences in the baseline clinical and angiographic characteristics in patients with low and intermediate to high SXscores are listed in Table 1. Previous medications, including antithrombotic treatment (aspirin and/or
Discussion
In the present study, we have shown that PLR at admission is an independent predictor of the prevalence of more complex coronary artery lesions (SXscore ≥23) in patients with ACS. In addition, our study has shown that PLR and SXscore predict in-hospital mortality in patients with ACS.
The SXscore is an anatomic scoring system based on CA that quantifies lesion severity and complexity and predicts poor cardiovascular outcomes, including mortality, in patients with ACS. In a previous study,
Disclosures
The authors have no conflicts of interest to disclose.
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