Coronary Artery DiseasePrediction of Coronary Artery Disease Severity Using CHADS2 and CHA2DS2-VASc Scores and a Newly Defined CHA2DS2-VASc-HS Score
Section snippets
Methods
This was a single-center study in which a total of 407 consecutive patients who were admitted for diagnostic CAG were prospectively enrolled. All study patients were referred for CAG as outpatients because of the symptoms suggestive of CAD and/or abnormal noninvasive stress tests based on exercise electrocardiographic testing or myocardial perfusion imaging test. Patients who had acute coronary syndrome, acute heart failure, acute ischemic stroke or transient ischemic attack (TIA), previous
Results
The study population consisted of 407 patients (mean age 61 ± 10 years, 113 women [28%]), of whom 87 had normal coronary arteries and were selected as the control group (group 1). The remaining 320 patients with coronary stenosis were further classified into 2 groups: 123 patients with CAD with stenosis of <50% as mild CAD group (group 2) and 197 patients with CAD with stenosis of ≥50% as severe CAD group (group 3). A comparison of the baseline demographics and characteristics of the 3 groups
Discussion
The major findings of the present report were (1) the CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-HS risk scores were increased in patients with mild and severe CAD, (2) the CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-HS scores were correlated significantly with the number of diseased vessels and Gensini score, and (3) the CHA2DS2-VASc-HS score was found to be the best score scheme to predict CAD severity in comparison of ROC curves and a score >2 may predict CAD severity.
Atherosclerotic cardiovascular
Disclosures
The authors have no conflicts of interest to disclose.
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