Heart failureImpact of Chronic Obstructive Pulmonary Disease on Long-Term Outcome of Patients Hospitalized for Heart Failure
Section snippets
Methods
The Somme is a department of France with a population of 555,551 inhabitants, according to the 1999 census. The Somme department has 11 healthcare establishments, managing patients with HF: 1 university hospital, 7 general hospitals, 2 private clinics, and 1 medium and long-stay unit. General practitioners, cardiologists, and internal physicians of these centers agreed to participate in this study.
Consecutive patients >20 years old hospitalized for a first episode of HF in any of these
Results
The study population comprised 799 patients (mean age 75 ± 12 years). One hundred fifty-six patients (19.5%) had a history of COPD. Table 1 presents the baseline characteristics of patients with and without COPD. Patients with COPD were predominantly men and more often smokers. Etiologies, prevalence of other noncardiac co-morbidities, and results of complementary investigations were comparable between the 2 groups.
Significant differences were observed between the 2 groups for prescription of
Discussion
This is the first study to specifically examine the prognostic impact of COPD in patients with HF. Our population, recruited from all healthcare establishments of the Somme department (France) in 2000, accurately reflects the modern demography of patients with HF. Relative survival curves diverged relatively late, after 1 year of follow-up, suggesting the low impact of COPD on short-term outcome. The long-term prognosis of patients with HF and COPD was poor with 5-year mortality as high as 69%,
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The importance of breathing not properly: Chronic obstructive pulmonary disease as a risk factor for rehospitalization in heart failure
2019, International Journal of CardiologyAcutely decompensated heart failure with chronic obstructive pulmonary disease: Clinical characteristics and long-term survival
2019, European Journal of Internal MedicineCitation Excerpt :Remarkably, the Kaplan-Meier method overestimated the absolute risk of death at 5 years by 15% in non-COPD and 4% in COPD patients, resulting in a reduced difference in mortality between COPD and non-COPD patients. The results of previous studies investigating the effect of COPD on mortality were not univocal [17–36] (Supplementary Table 1). Moreover, comparative evaluation of the results suggests a remarkable between-study heterogeneity in risk trajectories.
Influence of COPD on outcomes of patients hospitalized with heart failure: Analysis of the Spanish National Hospital Discharge Database (2001–2015)
2018, International Journal of CardiologyCitation Excerpt :However, among patients who survived to hospital discharge, those with previous diagnosis of COPD had a significantly higher risk of dying 1 to 5 years after discharge than patients without COPD. Similarly, Rusinaru et al. [31] did not find a significant impact of COPD on short-term survival, but they reported a significant association between COPD and long-term mortality. A possible explanation for these findings is that short-term mortality could be predominantly influenced by acute decompensated HF presenting characteristics, whereas COPD could be a stronger determinant of long-term outcomes [6,48].
This study was funded by a grant from the French Ministry of Health, Paris, France.