References for this review were identified by searches of Medline, from 1996 to 2002, in all languages. Search terms were “hepatitis B”, “hepatitis B virus”, “HBV”, and “HBV vaccination”.
ReviewGlobal control of hepatitis B virus infection
Section snippets
The virus
HBV was the first human hepatitis virus from which the proteins and genome could be clearly identified and characterised. In 1963, Blumberg et al5 studied polymorphisms of serum proteins, and discovered a previously unknown antigen—subsequently called “Australia antigen”—in an Australian aborigine whose blood sample formed a precipitin line with the serum of a multiply transfused haemophiliac. The antigen was later recognised by its specific association with hepatitis B. In 1970, Dane and
Global control of hepatitis B
Like other infectious agents, successful HBV infection is composed of three components: an infection source, a susceptible host, and an established route of infection (figure 2). The most effective way to control hepatitis B is therefore to prevent any susceptible person from virus infection, rather than treating those who are already infected. There are two major approaches. The first is to interrupt the route of transmission and the second is to immunise the susceptible host. Public-health
Search strategy and selection criteria
References (98)
- et al.
Virus-like particles in serum of patients with Australiaantigen-associated hepatitis
Lancet
(1970) Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B
Am J Pathol
(2000)- et al.
Immunology of hepatitis B infection
Lancet Infect Dis
(2002) - et al.
Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
Gastroenterology
(2000) - et al.
Chronic hepatitis B
Hepatology
(2001) - et al.
Acute exacerbations in Chinese patients with chronic hepatitis B virus (HBV) infection. Incidence, predisposing factors and etiology
J Hepatol
(1990) Acute flares in chronic hepatitis B: the natural and unnatural history of an immunologically mediated liver disease
Gastroenterology
(2001)- et al.
Hepatitis B e antigen-negative chronic hepatitis B
Hepatology
(2001) - et al.
Persistent hepatitis B virus: clinically significant or purely occult?
Hepatology
(2001) - et al.
Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan
Hepatology
(2001)
Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus
Hepatology
Hepatitis B genotypes and the response to interferon therapy
J Hepatol
Molecular characteristics of hepatitis B virus genotype A confer a higher response rate to interferon treatment
J Hepatol
Hepatitis B viral genotypes and lamivudine resistance
J Hepatol
20-fold increase in risk of lamivudine resistance in hepatitis B virus subtype adw
Lancet
A casecontrol study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C
Hepatology
Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity
J Hepatol
Adult hepatitis B vaccination using a novel triple antigen recombinant vaccine
Hepatology
Nationwide vaccination: a success story in Taiwan
Vaccine
Universal hepatitis B vaccination and the decreased mortality from fulminant hepatitis in infants in Taiwan
J Pediatr
Rationale for the infant and adolescent vaccination programmemes in Italy
Vaccine
Hepatitis B vaccination in infancy in The Gambia: protection against carriage at 9 years of age
Vaccine
Impact of hepatitis B immunisation as part of the EPI
Vaccine
Toward the global elimination of hepatitis B virus transmission
J Pediatr
Evaluation of a new hepatitis B triple-antigen vaccine in inadequate responders to current vaccines
Hepatology
Effect of hepatitis B virus mutants on efficacy of vaccination
Lancet
School-based hepatitis B vaccination programmeme and adolescent multiple sclerosis
Lancet
Persistence of immunologic memory for 13 years in recipients of a recombinant hepatitis B vaccine
Vaccine
The hepatitis B prevention education programmeme in Poland
Vaccine
Hepatitis B surface antigenemia at birth: a long-term follow-up study
J Pediatr
Strategies to prevent and control hepatitis B and C virus infections: a global perspective
Vaccine
Hepatitis B infection: pathogenesis and management
J Hepatol
Hepatitis B virus infection
Bull World Health Organ
Global programmeme for control of hepatitis B infection
Vaccine
From hepatitis to hepatoma: lessons from type B viral hepatitis
Science
Prevention of hepatitis B virus transmission by immunisation: an economic analysis of current recommendations
JAMA
A “new” antigen in leukemia sera
JAMA
DNA polymerase associated with human hepatitis B antigen
J Virol
DNA polymerase in the core of the human hepatitis B virus candidate
J Virol
The genome of hepatitis B virus
Annu Rev Microbiol
Hepatitis B Virus Infection
N Engl J Med
Overview of hepatitis B and C viruses
Genomic heterogeneity of hepatitis B virus in a 54 year old woman who contracted the infection through materno-fetal transmission
Jpn J Exp Med
Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes
J Gen Virol
Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene
Intervirology
A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness
J Gen Virol
Molecular epidemiology of hepatitis B viral serotypes and genotypes in Taiwan
J Biomed Sci
Natural history of chronic hepatitis B virus infection in adults with emphasis on the occurrence of cirrhosis and hepatocellular carcinoma
J Gastroenterol Hepatol
Acute exacerbation in chronic type B hepatitis: comparison between HBeAg and antibody-positive patients
Hepatology
Cited by (720)
The role of non-coding RNAs in the diagnosis of different stages (HCC, CHB, OBI) of hepatitis B infection
2023, Microbial PathogenesisApplications of piperazine scaffold in drug design
2023, Privileged Scaffolds in Drug DiscoveryImmune response to hepatitis B vaccine among children under 5 years in Africa: a meta-analysis
2024, Tropical Medicine and Health