Clinical investigationGray hair, baldness, and wrinkles in relation to myocardial infarction: The Copenhagen City Heart Study☆
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Beyond Venus and Mars: Examining gender-related differences in facial aging through the analysis of artworks
2023, Ethics, Medicine and Public HealthProtecting the Aging Genome
2020, Trends in Cell BiologyCitation Excerpt :This has been suggested to be an underlying pathogenic outcome in certain DNA repair diseases; for example, Fanconi anemia, Bloom syndrome, and Werner syndrome, where hypogonadism, anemia, and hair loss are prevalent [16,27,28]. These features are also seen in normal aging [29–31] and it is tempting to speculate that these features could be caused by similar issues with replication, particularly in stem cells (Figure 3D). If repair fails and damage accumulates, three outcomes can occur: cells can transform and become cancerous, cells can enter a nonproliferating state termed senescence, or cells can die through, for example, apoptosis.
The degree of hair graying as an independent risk marker for coronary artery disease, a CT coronary angiography study
2018, Egyptian Heart JournalCitation Excerpt :Similarly, multiple logistic regression analysis in previous study conducted by Kocaman et al.7 demonstrated that only diabetes mellitus (OR: 3.24, 95% CI: 1.017–10.31, p = 0.047), LDL cholesterol (OR: 1.01, 95% CI: 1.00–1.02, p = 0.029) and HWS (OR: 1.51, 95% CI: 1.05–2.17, p = 0.025) were independently related to the presence of CAD. On the other hand, in a study conducted by Christoffersen et al.27 graying of hair did not associate with risk of ischemic heart disease or MI after multi-factorial adjustment (baldness, earlobe crease, and xanthelasmata), although in the 12-year follow-up of the same study, an association with MI was found in men.8 Today, it is known that CVRFs, especially in combination, cause premature atherosclerosis.
Visible aging signs as risk markers for ischemic heart disease: Epidemiology, pathogenesis and clinical implications
2016, Ageing Research ReviewsCitation Excerpt :In our prospective study with 35 years of follow-up of 10,885 individuals from the Danish general population prominent facial wrinkles did not associate with risk of ischemic heart disease or myocardial infarction after adjustment for potential confounders (Christoffersen et al., 2014). These results were similar to results obtained in the same study after 12 years of follow-up (Schnohr et al., 1995). An association between elastin morphology in the skin and Framingham cardiovascular risk score was found in a recent study (Waaijer et al., 2012).
Association between androgenetic alopecia and periodontitis
2023, Journal of Periodontal ResearchYounger facial looks are associate with a lower likelihood of several age-related morbidities in the middle-aged to elderly
2023, British Journal of Dermatology
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Supported by grants from The Danish Heart Foundation.