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HIV in adolescents

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Abstract

Adolescence is a time of dramatic physical, emotional, cognitive, and social change that brings new vulnerabilities. Youth represent half of all new HIV infections in the United States and the rest of the world. The number of newly infected adolescents who acquire the disease behaviorally and the number of perinatally infected children surviving into adolescence have both contributed to this growth. This article reviews the most recent epidemiology of HIV/AIDS in adolescents, gives guidance on clinical practice, including medical and psychosocial care, and examines prevention issues, including counseling and testing, which are needed to make programs effective for youth.

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References and Recommended Reading

  1. Futterman DC: HIV and AIDS in adolescents. Adolesc Med 2004, 15:369–391. An up-to-date review of HIV and AIDS in adolescents that discusses the epidemiology, clinical practice, and prevention issues relevant both to adolescents and clinicians.

    Article  Google Scholar 

  2. Centers for Disease Control and Prevention: HIV/AIDS Surveillance Report, 2003 (Vol.13).Atlanta, GA: Department of Health and Human Services, Centers for Disease Control and Prevention; 2003:1–46.

    Google Scholar 

  3. Joint United Nations Program on HIV/AIDS, World Health Organization:Report on the Global Epidemic. Geneva: World Health Organization; 2002.

    Google Scholar 

  4. Centers for Disease Control and Prevention: Surveillance Summaries, May 21, 2004. MMWR Morb Mortal Wkly Rep, 53:SS-2.

  5. Dodds S, Blakley T, Lizzotte JM, et al.: Retention, adherence, and compliance: special needs of HIV-infected adolescent girls and young women. J Adolesc Health 2003, 33(Suppl 2):39–45. An in-depth study of the gender-specific needs of 21 HIV-positive adolescent women in care is reviewed. The authors make practical recommendations of how to assist young people with HIV with improving retention in, adherence to, and compliance with HIV care.

    Article  PubMed  Google Scholar 

  6. Kunins H, Hein K, Futterman D, et al.: A guide to adolescent HIV/AIDS program development. J Adolesc Health 1993, 14(Suppl 5):1–168.

    Google Scholar 

  7. Working Group on Antiretroviral Therapy and Medical Management of HIV-Infected Children: Guidelines for the use of antiretroviral agents in pediatric HIV infection, March 24, 2005. http://aidsinfo.nih.gov/. Accessed June 1, 2005.

  8. Panel on Clinical Practices for Treatment of HIV Infection: Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents, April 7, 2005. http://aidsinfo. nih.gov/. Accessed June 1, 2005. This regularly updated document gives guidelines on the current evidence-based understanding of antiretroviral medication used in the treatment of HIV-infected adults and adolescents.

  9. Rudy BJ, Crowley-Nowick PA, Douglas SD: Immunology and the REACH study: HIV immunology and preliminary findings. J Adolesc Health 2001, 29(Suppl 3):39–48.

    Article  PubMed  CAS  Google Scholar 

  10. Flynn PM, Rudy BJ, Douglas SD, et al.: Virologic and immunologic outcomes after 24 weeks in HIV type 1-infected adolescents receiving highly active antiretroviral therapy. J Infect Dis 2004, 190:271–279. A Pediatric Acquired Immunodeficiency Syndrome Clinical Trials Group (PACTG) study conducted at 28 sites looking at the virologic and immunologic response over a 16- to 24-week time period to antiretroviral treatment in 120 behaviorally infected adolescents with HIV.

    Article  PubMed  CAS  Google Scholar 

  11. Schietinger H, Sawyer M, Futterman D, et al.: Helping adolescents with HIV adhere to HAART. TREAT monograph. ftp:// ftp.hrsa.gov/hab/TeenHAART.pdf. Accessed June 3, 2005.

  12. Centers for Disease Control and Prevention: Treating opportunistic infections among HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America. MMWR Morb Mortal Wkly Rep 2004, 53:1–120.

    Google Scholar 

  13. Murphy DA, Sarr M, Durako SJ, et al.: Barriers to HAART adherence among human immunodeficiency virus-infected adolescents. Arch Pediatr Adolesc Med 2003, 157:249–255. A study using the Reaching for Excellence in Adolescent Care and Health (REACH) cohort of HIV-infected adolescents at 13 sites in US cities. This study utilized structured interviews in adolescents who were prescribed antiretroviral therapy to assess barriers to adherence.

    Article  PubMed  Google Scholar 

  14. Burstein GR, Lowry R, Klein JD, et al.: Missed opportunities for sexually transmitted diseases, human immunodeficiency virus, and pregnancy prevention services during adolescent health supervision visits. Pediatrics 2003, 111:996–1001.

    Article  PubMed  Google Scholar 

  15. Hoppe MJ, Graham L, Wilsdon A, et al.: Teens speak out about HIV/AIDS: focus group discussions about risk and decisionmaking. J Adolesc Health 2004, 35:345e 27–35. The authors utilized same-sex focus groups with 92 high school students to explore decision-making around sex and condom use. Based on the outcomes, the authors make recommendations regarding applicable HIV education.

    Google Scholar 

  16. Robin L, Dittus P, Whitaker D, et al.: Behavioral interventions to reduce incidence of HIV, STD, and pregnancy among adolescents: a decade in review. J Adolesc Health 2004, 34:3–26. A comprehensive review of adolescent sexual risk-reduction programs that have been previously evaluated are described and analyzed. Overall factors of program effectiveness with regard to decreasing sexual risk behaviors are discussed.

    Article  PubMed  Google Scholar 

  17. Ellickson PL, Collins RL, Bogart LM, et al.: Scope of HIV risk and co-occurring psychosocial health problems among young adults: violence, victimization, and substance use. J Adolesc Health 2005, 36:401–409. Study utilizing the RAND Adolescent/Young Adult Panel (longitudinal West Coast cohort of 7th graders followed for 10 years) to look at HIV risk (sexual) in association with violence, victimization, and substance use.

    Article  PubMed  Google Scholar 

  18. Futterman D, Peralta L, Rudy B, et al.: The ACCESS (Adolescents Connected to Care, Evaluation, and Special Services) project: social marketing to promote HIV testing to adolescents, methods and first year results from a six city campaign. J Adolesc Health 2001, 29(Suppl 3):19–29.

    Article  PubMed  CAS  Google Scholar 

  19. Centers for Disease Control and Prevention: Advancing HIV prevention: new strategies for a changing epidemic. MMWR Morb Mortal Rep Wkly 2003, 52:329–332.

    Google Scholar 

  20. Valleroy LA, MacKellar DA, Karon JM, et al.: HIV prevalence and associated risks in young men who have sex with men. Young men’s survey study group. JAMA 2000, 284:198–204.

    Article  PubMed  CAS  Google Scholar 

  21. BisnoAL: Acute pharyngitis. New Engl J Med 2001, 344:205–211.

    Article  PubMed  CAS  Google Scholar 

  22. Vanhems P, Dassa C, Lambert J, et al.: Comprehensive classification of symptoms and signs reported among 218 patients with acute HIV-1 infection. J Acquir Immune Defic Syndr 1999, 21:99–106.

    PubMed  CAS  Google Scholar 

  23. Kahn JO, Walker BD: Acute human immunodeficiency virus type 1 infection. New Engl J Med 1998, 339:33–39.

    Article  PubMed  CAS  Google Scholar 

  24. Centers for Disease Control and Prevention: Antiretroviral post exposure prophylaxis, injection-drug use, or other nonoccupational exposure to HIV in the United States: recommendations from the United States Department of Health and Human Services. Morb Mortal Wkly Rep 2005, 54:1–20.

    Google Scholar 

  25. Rotheram-Borus MJ, Futterman DC: Promoting early detection of human immunodeficiency virus infection among adolescents. Arch Pediatr Adolesc Med 2000, 154:435–439.

    PubMed  CAS  Google Scholar 

  26. Bell DN, Martinez J, Botwinick G, et al.: Case finding for HIV-positive youth: a special type of hidden population. J Adolesc Health 2003, 33(Suppl 2):10–22.

    Article  PubMed  Google Scholar 

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Catallozzi, M., Futterman, D.C. HIV in adolescents. Curr Infect Dis Rep 7, 401–405 (2005). https://doi.org/10.1007/s11908-005-0015-z

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  • DOI: https://doi.org/10.1007/s11908-005-0015-z

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