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Long-term Weight Regain after Gastric Bypass: A 5-year Prospective Study

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Abstract

Background

A certain weight gain occurs after obesity surgery compared to the lower weight usually observed between 18 and 24 months postsurgery. The objective of this study was to evaluate weight regain in patients submitted to gastric bypass over a 5-year follow-up period.

Materials and Methods

A longitudinal prospective study was conducted on 782 obese patients of both genders. Only patients with at least 2 years of surgery were included. The percentage of excess body mass index (BMI) loss at 24, 36, 48, and 60 months postsurgery was compared to the measurements obtained at 18 months after surgery. Surgical therapeutic failure was also evaluated.

Results

Percent excess BMI loss was significant up to 18 months postsurgery (p < 0.001), with a mean difference in BMI of 1.06 kg/m2 compared to 12 months postsurgery. Percent BMI loss was no longer significant after 24 months, and weight regain became significant within 48 months after surgery (p < 0.01). Among the patients who presented weight regain, a mean 8% increase was observed within 60 months compared to the lowest weight obtained at 18 months after surgery. The percentage of surgical failure was higher in the superobese group at all times studied, reaching 18.8% at 48 months after surgery.

Conclusion

Weight regain was observed within 24 months after surgery in approximately 50% of patients. Both weight regain and surgical failure were higher in the superobese group. Studies in regard to metabolic and hormonal mechanisms underlying weight regain might elucidate the causes of this finding.

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References

  1. Hsu LK, Betancourt S, Sullivan SP. Eating disturbances before and after vertical banded gastroplasty: a pilot study. Int J Eat Disord. 1996;19(1):23–34.

    Article  PubMed  CAS  Google Scholar 

  2. Spitzer RR, Devleu M, Waish BT et al. Binge eating disorder: a multisite field trial of the diagnostic criteria. Int J Eat Disord. 1992;11:191–203.

    Article  Google Scholar 

  3. Malone M, Alger-Mayer S. Binge status and quality of life after gastric bypass surgery: a one-year study. Obesity Res. 2004;12:473–81.

    Article  Google Scholar 

  4. Buchwald H, Avidor Y, Braunwald E et al. Bariatric surgery. A systematic review and meta-analysis. JAMA. 2004;13:1724–37.

    Article  Google Scholar 

  5. Hsu LK, Benotti PN, Dwyer J, Roberts SB, Saltzman E, Shikora S et al. Nonsurgical factors that influence the outcome of bariatric surgery: a review. Psychosom Med. 1998;60:338–46.

    PubMed  CAS  Google Scholar 

  6. Brolin RE, Kenler HA, Gorman JH, Cody RP. Long-limb gastric bypass in the superobese. A prospective randomized study. Ann Surg. 1992;215:387–95.

    Article  PubMed  CAS  Google Scholar 

  7. Capella JF, Capella RF. The weight reduction operation of choice: Vertical banded gastroplasty or gastric bypass? Am J Surg. 1996;171:74–9.

    Article  PubMed  CAS  Google Scholar 

  8. Fobi MA, Lee H, Igwe D Jr, Felahy B, James E, Stanczyk M et al. Revision of failed gastric bypass to distal Roux-en-Y gastric bypass: a review of 65 cases. Obes Surg. 2001;11:190–5.

    Article  PubMed  CAS  Google Scholar 

  9. Biron S, Hould FS, Lebel S, Marceau S, Lescelleur O, Simard S et al. Twenty years of biliopancreatic diversion: What is the goal of the surgery? Obes Surg. 2004;14:160–4.

    Article  PubMed  Google Scholar 

  10. Deitel M, Gawdat K, Melissas J. Reporting weight loss 2007—Editorial. Obes Surg. 2007;565–8.

  11. MacLean LD, Rhode BM, Nohr LW. Late outcome of isolated gastric bypass. Ann Surg. 1999;231:524–8.

    Article  Google Scholar 

  12. Saunders R. Binge eating in gastric bypass patients before surgery. Obes Surg. 1999;9:72–6.

    Article  PubMed  CAS  Google Scholar 

  13. Cook CM, Edwards C. Success habits of long-term gastric bypass patients. Obes Surg. 1999;9:80–2.

    Article  PubMed  CAS  Google Scholar 

  14. Signore C. Beyond Change, “Information Regarding Obesity Surgery”. September 2004. JKS Associates 43494 Woodward Avenue, Suite 108 Bloomfield Hills, MI 48302-0567. ISSN 1548-260X.

  15. Adami GF, Gandolfo P, Bauer B, Scopinaro N. Binge eating in massively obese patients undergoing bariatric surgery. In J Eat Disord. 1995;17:45–50.

    Article  CAS  Google Scholar 

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Correspondence to Daniéla Oliveira Magro.

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Magro, D.O., Geloneze, B., Delfini, R. et al. Long-term Weight Regain after Gastric Bypass: A 5-year Prospective Study. OBES SURG 18, 648–651 (2008). https://doi.org/10.1007/s11695-007-9265-1

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  • DOI: https://doi.org/10.1007/s11695-007-9265-1

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