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Biopsy techniques and yields in diagnosing primary intraocular lymphoma

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Abstract

A review of current biopsy techniques that are used in obtaining specimens from which to make a diagnosis of primary intraocular lymphoma (PIOL) is presented. Methods for obtaining and subsequently testing vitrectomy specimens are discussed. In addition, the yields of external and internal approaches for obtaining chorioretinal tissue, and diagnostic vitrectomies, are reviewed.

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Abbreviations

CSF:

cerebrospinal fluid

PCNSL:

primary central nervous system lymphoma

PIOL:

primary intraocular lymphoma

PCR:

polymerase chain reaction amplification.

RPE:

retinal pigment epithelium

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Acknowledgement

Support: The NEI intramural research program

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Authors and Affiliations

  1. Immunopathology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Building 10, Room 10N103, MSC 1857, 10 Center Drive, Bethesda, MD, 20892-1857, USA

    John A. Gonzales & Chi-Chao Chan

  2. Howard Hughes Medical Institute, Chevy Chase, MD, USA

    John A. Gonzales

  3. Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    John A. Gonzales

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  1. John A. Gonzales
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  2. Chi-Chao Chan
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Correspondence to Chi-Chao Chan.

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Gonzales, J.A., Chan, CC. Biopsy techniques and yields in diagnosing primary intraocular lymphoma. Int Ophthalmol 27, 241–250 (2007). https://doi.org/10.1007/s10792-007-9065-6

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  • DOI: https://doi.org/10.1007/s10792-007-9065-6

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