Skip to main content

Advertisement

Log in

Time trends and ethnic patterns of childhood nephrotic syndrome in Yorkshire, UK

  • Original Article
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

Abstract.

Against the background of the increasing incidence of many immune mediated childhood conditions, this study aimed to identify recent time trends and ethnic patterns of childhood nephrotic syndrome. A population-based cohort of children (0–15 years) diagnosed according to strict criteria with nephrotic syndrome (NS) was ascertained within the northern UK region of Yorkshire between 1987 and 1998. South Asian ethnicity was assigned based on the child’s full name using a dedicated computer algorithm and expert individual checks. NS was diagnosed in 194 children, 170 (88%) of whom were steroid sensitive. The incidence of steroid sensitive NS was 2.0/100,000 pyrs (95% CI 1.7–2.3), peaking in 1–4 year olds (4.1/100,000 pyrs). Over the 12-year study period incidence rates of steroid sensitive NS were fairly stable although south Asian children displayed significantly higher rates than non-south Asians (P<0.01). The size of our population-based series reflects the relative rarity of paediatric nephrotic syndrome but is nonetheless recent and includes larger numbers than previous reports. The absence of any increase in incidence over the last decade contrasts with other paediatric immune mediated conditions such as asthma and diabetes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

Authors

Additional information

Received: 2 May 2001 / Revised: 26 July 2001 / Accepted: 26 July 2001

Rights and permissions

Reprints and permissions

About this article

Cite this article

McKinney, P., Feltbower, R., Brocklebank, J. et al. Time trends and ethnic patterns of childhood nephrotic syndrome in Yorkshire, UK. Pediatr Nephrol 16, 1040–1044 (2001). https://doi.org/10.1007/s004670100021

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004670100021

Navigation