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Image evaluation of endolymphatic space in fluctuating hearing loss without vertigo

  • Otology
  • Published:
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Abstract

The objective of the present study was to investigate endolymphatic space images in patients with fluctuating hearing loss without vertigo, and to elucidate its underlying pathophysiology. Eight patients with fluctuating hearing loss without vertigo were included in this study. 3T MRI was taken, 24 h after intratympanic injection of gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Electrocochleography and VEMP tests were performed to evaluate cochlear and vestibular functions. Endolymphatic hydrops were observed both in the cochlea and in the vestibule of all eight patients. Three patients out of six whose summating potential/action potential (SP/AP) ratio was recordable showed an elevation of SP/AP ratio. In the two patients with remarkable endolymphatic hydrops in the vestibule, VEMP was absent from the affected ear. In conclusion, 3T MRI after intratympanic injection of Gd-DTPA revealed endolymphatic hydrops both in the cochlea and in the vestibule in the patients with fluctuating hearing loss without vertigo.

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Acknowledgments

This study was supported by research grants from the Ministry of Health, Labor, and Welfare and from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

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Authors and Affiliations

  1. Department of Otorhinolaryngology, Graduate School of Medicine, Nagoya University, 65, Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan

    Masaaki Teranishi, Naomi Katayama, Makoto Sugiura, Seiichi Nakata, Michihiko Sone & Tsutomu Nakashima

  2. Department of Radiology, Graduate School of Medicine, Nagoya University, Nagoya, Japan

    Shinji Naganawa

Authors
  1. Masaaki Teranishi
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  2. Shinji Naganawa
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  3. Naomi Katayama
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  4. Makoto Sugiura
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  5. Seiichi Nakata
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  6. Michihiko Sone
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  7. Tsutomu Nakashima
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Correspondence to Masaaki Teranishi.

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Teranishi, M., Naganawa, S., Katayama, N. et al. Image evaluation of endolymphatic space in fluctuating hearing loss without vertigo. Eur Arch Otorhinolaryngol 266, 1871–1877 (2009). https://doi.org/10.1007/s00405-009-0989-5

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  • DOI: https://doi.org/10.1007/s00405-009-0989-5

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