Intensive & critical care

Short-term and long-term survival in critical patients treated by helicopter emergency medical services in Finland: a registry study of 36 715 patients
Johannes Björkman, Päivi Laukkanen-Nevala, Anna Olkinuora, Ilkka Pulkkinen, Jouni Nurmi

BMJ Open Feb 2021, 11 (2) e045642; DOI: 10.1136/bmjopen-2020-045642
Cardiovascular risk factors and COVID-19 outcomes in hospitalised patients: a prospective cohort study
Didier Collard, Nick S Nurmohamed, Yannick Kaiser, Laurens F Reeskamp, Tom Dormans, Hazra Moeniralam, Suat Simsek, Renee Douma, Annet Eerens, Auke C Reidinga, Paul W G Elbers, Martijn Beudel, Liffert Vogt, Erik S G Stroes, Bert-Jan H van den Born

BMJ Open Feb 2021, 11 (2) e045482; DOI: 10.1136/bmjopen-2020-045482
The timing of continuous renal replacement therapy initiation in sepsis-associated acute kidney injury in the intensive care unit: the CRTSAKI Study (Continuous RRT Timing in Sepsis-associated AKI in ICU): study protocol for a multicentre, randomised controlled trial
Wei-yan Chen, Li-hua Cai, Zhen-hui Zhang, Li-li Tao, Yi-chao Wen, Zhi-bo Li, Li Li, Yun Ling, Jian-wei Li, Rui Xing, Xue-yan Liu, Zhuan-di Lin, Zhe-tong Deng, Shou-hong Wang, Qin-han Lin, Dun-rong Zhou, Zhi-jie He, Xu-ming Xiong

BMJ Open Feb 2021, 11 (2) e040718; DOI: 10.1136/bmjopen-2020-040718
Effectiveness of a sepsis programme in a resource-limited setting: a retrospective analysis of data of a prospective observational study (Ubon-sepsis)
Suchart Booraphun, Viriya Hantrakun, Suwatthiya Siriboon, Chaiyaporn Boonsri, Pulyamon Poomthong, Bung-Orn Singkaew, Oratai Wasombat, Parinya Chamnan, Ratapum Champunot, Kristina Rudd, Nicholas P J Day, Arjen M Dondorp, Prapit Teparrukkul, Timothy Eoin West, Direk Limmathurotsakul

BMJ Open Feb 2021, 11 (2) e041022; DOI: 10.1136/bmjopen-2020-041022
Association between cardiometabolic disease and severe COVID-19: a nationwide case–control study of patients requiring invasive mechanical ventilation
Per Svensson, Robin Hofmann, Henrike Häbel, Tomas Jernberg, Per Nordberg

BMJ Open Feb 2021, 11 (2) e044486; DOI: 10.1136/bmjopen-2020-044486
Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
Emanuela Biagioni, Martina Tosi, Giorgio Berlot, Giacomo Castiglione, Alberto Corona, Maria Giovanna De Cristofaro, Abele Donati, Paolo Feltracco, Francesco Forfori, Fiorentino Fragranza, Patrizia Murino, Ornella Piazza, Livio Tullo, Giacomo Grasselli, Roberto D'Amico, Massimo Girardis

BMJ Open Feb 2021, 11 (2) e036616; DOI: 10.1136/bmjopen-2019-036616
Safety and feasibility of using acellular sterile filtered amniotic fluid as a treatment for patients with COVID-19: protocol for a randomised, double-blinded, placebo-controlled clinical trial
Joseph E Tonna, Jan Pierce, Nathan Hatton, Giavonni Lewis, John D Phillips, Alyssa Messina, Chloe R Skidmore, Kirsten Taylor, Craig H Selzman

BMJ Open Feb 2021, 11 (2) e045162; DOI: 10.1136/bmjopen-2020-045162
Is there a sex difference in mortality rates for deaths occurring in paediatric intensive care units? Systematic literature review protocol
Ofran Almossawi, Amanda Friend, Luigi Palla, Richard Feltbower, Bianca De Stavola

BMJ Open Feb 2021, 11 (2) e046794; DOI: 10.1136/bmjopen-2020-046794
Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis
Bilal Akhter Mateen, Harrison Wilde, John M Dennis, Andrew Duncan, Nick Thomas, Andrew McGovern, Spiros Denaxas, Matt Keeling, Sebastian Vollmer

BMJ Open Jan 2021, 11 (1) e042945; DOI: 10.1136/bmjopen-2020-042945
Development and validation of a prognostic nomogram for myocardial infarction patients in intensive care units: a retrospective cohort study
Qi Guo, Maoxiong Wu, Hongwei Li, Huijun Ouyang, Runlu Sun, Junjie Wang, Zhaoyu Liu, Jingfeng Wang, Yuling Zhang

BMJ Open Dec 2020, 10 (12) e040291; DOI: 10.1136/bmjopen-2020-040291

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