Immunology

Systematic review and meta-analysis of the association between peripheral inflammatory cytokines and generalised anxiety disorder
Harry Costello, Rebecca L Gould, Esha Abrol, Robert Howard

BMJ Open Jul 2019, 9 (7) e027925; DOI: 10.1136/bmjopen-2018-027925
Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study
Terrance J Wade, Deborah D O’Leary, Kylie S Dempster, Adam J MacNeil, Danielle S Molnar, Jennifer McGrath, John Cairney

BMJ Open Jul 2019, 9 (7) e030339; DOI: 10.1136/bmjopen-2019-030339
Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial
Martin Geoffrey Thomas, Carrie Bayliss, Simon Bond, Francis Dowling, James Galea, Vipul Jairath, Christopher Lamb, Christopher Probert, Elizabeth Timperley-Preece, Alastair Watson, Lynne Whitehead, John G Williams, Miles Parkes, Arthur Kaser, Tim Raine

BMJ Open Feb 2019, 9 (2) e023765; DOI: 10.1136/bmjopen-2018-023765
Selective citation in the literature on the hygiene hypothesis: a citation analysis on the association between infections and rhinitis
Bram Duyx, Miriam J E Urlings, Gerard M H Swaen, Lex M Bouter, Maurice P Zeegers

BMJ Open Feb 2019, 9 (2) e026518; DOI: 10.1136/bmjopen-2018-026518
Bortezomib in antibody-mediated autoimmune diseases (TAVAB): study protocol for a unicentric, non-randomised, non-placebo controlled trial
Siegfried Kohler, Stefanie Märschenz, Ulrike Grittner, Tobias Alexander, Falk Hiepe, Andreas Meisel

BMJ Open Jan 2019, 9 (1) e024523; DOI: 10.1136/bmjopen-2018-024523
Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study
Ravi Lokwani, Peter A B Wark, Katherine J Baines, Daniel Barker, Jodie L Simpson

BMJ Open Jan 2019, 9 (1) e024330; DOI: 10.1136/bmjopen-2018-024330
Adjuvant rituximab, a potential treatment for the young patient with Graves’ hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial
Michael Cole, Ann Marie Hynes, Denise Howel, Lesley Hall, Mario Abinun, Amit Allahabadia, Timothy Barrett, Kristien Boelaert, Amanda J Drake, Paul Dimitri, Jeremy Kirk, Nicola Zammitt, Simon Pearce, Tim Cheetham

BMJ Open Jan 2019, 9 (1) e024705; DOI: 10.1136/bmjopen-2018-024705
PRedicting Outcomes For Crohn’s dIsease using a moLecular biomarkEr (PROFILE): protocol for a multicentre, randomised, biomarker-stratified trial
Miles Parkes, Nurulamin M Noor, Francis Dowling, Harvey Leung, Simon Bond, Lynne Whitehead, Sara Upponi, Paul Kinnon, Andrew P Sandham, Paul A Lyons, Eoin F McKinney, Kenneth G C Smith, James C Lee

BMJ Open Dec 2018, 8 (12) e026767; DOI: 10.1136/bmjopen-2018-026767
Association of IL-10 and IL-10RA single nucleotide polymorphisms with the responsiveness to HBV vaccination in Chinese infants of HBsAg(+)/HBeAg(−) mothers: a nested case–control study
Simin Wen, Yanhua Wu, Yuchen Pan, Mengzhuo Cao, Dan Zhao, Chong Wang, Chuan Wang, Fei Kong, Jie Li, Junqi Niu, Jing Jiang

BMJ Open Nov 2018, 8 (11) e022334; DOI: 10.1136/bmjopen-2018-022334
Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE): a prospective birth cohort in northern Sweden
Malin Barman, Fiona Murray, Angelina I Bernardi, Karin Broberg, Sven Bölte, Bill Hesselmar, Bo Jacobsson, Karin Jonsson, Maria Kippler, Hardis Rabe, Alastair B Ross, Fei Sjöberg, Nicklas Strömberg, Marie Vahter, Agnes E Wold, Ann-Sofie Sandberg, Anna Sandin

BMJ Open Oct 2018, 8 (10) e022013; DOI: 10.1136/bmjopen-2018-022013

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