Immunology

Rescuing Cancer Immunity by Plasma Exchange in Metastatic Melanoma (ReCIPE-M1): protocol for a single-institution, open-label safety trial of plasma exchange to clear sPD-L1 for immunotherapy
Tara M Davidson, Nathan Foster, Fabrice Lucien, Svetomir Markovic, Haidong Dong, Jeffrey L Winters, Sean S Park, Jacob J Orme

BMJ Open May 2022, 12 (5) e050112; DOI: 10.1136/bmjopen-2021-050112
Personalised immunotherapy in sepsis: a scoping review protocol
Marleen A Slim, Niels van Mourik, Joanna C Dionne, Simon J W Oczkowski, M G Netea, Peter Pickkers, Evangelos J Giamarellos-Bourboulis, Marcella C A Müller, Tom van der Poll, W Joost Wiersinga, Alexander P J Vlaar, Lonneke A van Vught

BMJ Open May 2022, 12 (5) e060411; DOI: 10.1136/bmjopen-2021-060411
Effects of 3 months of multi-nutrient supplementation on the immune system and muscle and respiratory function of older adults in aged care (The Pomerium Study): protocol for a randomised controlled trial
Ahmed Al Saedi, Ben Kirk, Sandra Iuliano, Jesse Zanker, Sara Vogrin, Lata Jayaram, Shane Thomas, Christine Golding, Diana Navarro-Perez, Petra Marusic, Sean Leng, Ralph Nanan, Gustavo Duque

BMJ Open May 2022, 12 (5) e059075; DOI: 10.1136/bmjopen-2021-059075
Therapies for Long COVID in non-hospitalised individuals: from symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study)
Shamil Haroon, Krishnarajah Nirantharakumar, Sarah E Hughes, Anuradhaa Subramanian, Olalekan Lee Aiyegbusi, Elin Haf Davies, Puja Myles, Tim Williams, Grace Turner, Joht Singh Chandan, Christel McMullan, Janet Lord, David C Wraith, Kirsty McGee, Alastair K Denniston, Thomas Taverner, Louise J Jackson, Elizabeth Sapey, George Gkoutos, Krishna Gokhale, Edward Leggett, Clare Iles, Christopher Frost, Gary McNamara, Amy Bamford, Tom Marshall, Dawit T Zemedikun, Gary Price, Steven Marwaha, Nikita Simms-Williams, Kirsty Brown, Anita Walker, Karen Jones, Karen Matthews, Jennifer Camaradou, Michael Saint-Cricq, Sumita Kumar, Yvonne Alder, David E Stanton, Lisa Agyen, Megan Baber, Hannah Blaize, Melanie Calvert

BMJ Open Apr 2022, 12 (4) e060413; DOI: 10.1136/bmjopen-2021-060413
Prevalence and predictors of influenza vaccination in long-term care homes: a cross-national retrospective observational study
Reem T Mulla, Luke Andrew Turcotte, Nathalie IH Wellens, Milou J Angevaare, Julie Weir, Micaela Jantzi, Paul C Hébert, George A Heckman, Hein van Hout, Nigel Millar, John P Hirdes

BMJ Open Apr 2022, 12 (4) e057517; DOI: 10.1136/bmjopen-2021-057517
Prospective observational study of the role of the microbiome in BCG responsiveness prediction (SILENT-EMPIRE): a study protocol
Uwe Bieri, Michael Scharl, Silvan Sigg, Barbara Maria Szczerba, Yasser Morsy, Jan Hendrik Rüschoff, Peter Hans Schraml, Michael Krauthammer, Lukas John Hefermehl, Daniel Eberli, Cédric Poyet

BMJ Open Apr 2022, 12 (4) e061421; DOI: 10.1136/bmjopen-2022-061421
Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients
Matthew Oliver Brook, Joanna Hester, William Petchey, Ines Rombach, Susan Dutton, Matthew James Bottomley, Joanna Black, Seetha Abdul-Wahab, Andrew Bushell, Giovanna Lombardi, Kathryn Wood, Peter Friend, Paul Harden, Fadi Issa

BMJ Open Apr 2022, 12 (4) e061864; DOI: 10.1136/bmjopen-2022-061864
Effects of bDMARDs on quality of life in patients with psoriatic arthritis: meta-analysis
Yuqiong Lu, Zhanjing Dai, Yun Lu, Feng Chang

BMJ Open Apr 2022, 12 (4) e058497; DOI: 10.1136/bmjopen-2021-058497
Safety and immunogenicity of an inactivated virus particle vaccine for SARS-CoV-2, BIV1-CovIran: findings from double-blind, randomised, placebo-controlled, phase I and II clinical trials among healthy adults
Minoo Mohraz, Mohammadreza Salehi, Payam Tabarsi, Mohsen Abbasi-Kangevari, Seyyed-Hadi Ghamari, Erfan Ghasemi, Maryam Amini Pouya, Negar Rezaei, Naser Ahmadi, Kazem Heidari, Mohammad-Reza Malekpour, Mojtaba Nasiri, Ali Akbar Amirzargar, Sahar Saeedi Moghaddam, Bagher Larijani, Hamed Hosseini

BMJ Open Apr 2022, 12 (4) e056872; DOI: 10.1136/bmjopen-2021-056872
Effect of acute aerobic exercise before immunotherapy and chemotherapy infusion in patients with metastatic non-small-cell lung cancer: protocol for the ERICA feasibility trial
Manon Gouez, Olivia Pérol, Maurice Pérol, Christophe Caux, Christine Ménétrier-Caux, Marine Villard, Thierry Walzer, Lidia Delrieu, Pierre Saintigny, Philippe Marijnen, Vincent Pialoux, Béatrice Fervers

BMJ Open Apr 2022, 12 (4) e056819; DOI: 10.1136/bmjopen-2021-056819

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