Immunology

Evaluating the role of paternal factors in aetiology and prognosis of recurrent pregnancy loss: study protocol for a hospital-based multicentre case–control study and cohort study (REMI III project)
Nadia du Fossé, Marie-Louise van der Hoorn, Michael Eikmans, Sebastiaan Heidt, Saskia le Cessie, Annemarie Mulders, Jan van Lith, Eileen Lashley

BMJ Open Nov 2019, 9 (11) e033095; DOI: 10.1136/bmjopen-2019-033095
Comparative efficacy of 13 immunosuppressive agents for idiopathic membranous nephropathy in adults with nephrotic syndrome: a systematic review and network meta-analysis
Qiyan Zheng, Huisheng Yang, Weijing Liu, Weiwei Sun, Qing Zhao, Xiaoxiao Zhang, Huanan Jin, Luying Sun

BMJ Open Sep 2019, 9 (9) e030919; DOI: 10.1136/bmjopen-2019-030919
Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS): a harmonised study protocol for two phase I clinical trials comparing intradermal and intranodal cell administration
Barbara Willekens, Silvia Presas-Rodríguez, MJ Mansilla, Judith Derdelinckx, Wai-Ping Lee, Griet Nijs, Maxime De Laere, Inez Wens, Patrick Cras, Paul Parizel, Wim Van Hecke, Annemie Ribbens, Thibo Billiet, Geert Adams, Marie-Madeleine Couttenye, Juan Navarro-Barriuso, Aina Teniente-Serra, Bibiana Quirant-Sánchez, Ascensión Lopez-Diaz de Cerio, Susana Inogés, Felipe Prosper, Anke Kip, Herman Verheij, Catharina C Gross, Heinz Wiendl, Marieke (SM) Van Ham, Anja Ten Brinke, Ana Maria Barriocanal, Anna Massuet-Vilamajó, Niel Hens, Zwi Berneman, Eva Martínez-Cáceres, Nathalie Cools, Cristina Ramo-Tello

BMJ Open Sep 2019, 9 (9) e030309; DOI: 10.1136/bmjopen-2019-030309
Relationships between the clinical phenotypes and genetic variants associated with the immunological mechanism in childhood idiopathic nephrotic syndrome: protocol for a prospective observational single-centre cohort study
Han Chan, Hao Lee, Xia Yang, Jingzhi Wang, Xueying Yang, Chun Gan, Han Xiao, Qianqian Li, Jia Jiao, Daoqi Wu, Gaofu Zhang, Mo Wang, Haiping Yang, Qiu Li

BMJ Open Aug 2019, 9 (8) e028717; DOI: 10.1136/bmjopen-2018-028717
Systematic review and meta-analysis of the association between peripheral inflammatory cytokines and generalised anxiety disorder
Harry Costello, Rebecca L Gould, Esha Abrol, Robert Howard

BMJ Open Jul 2019, 9 (7) e027925; DOI: 10.1136/bmjopen-2018-027925
Adverse childhood experiences (ACEs) and cardiovascular development from childhood to early adulthood: study protocol of the Niagara Longitudinal Heart Study
Terrance J Wade, Deborah D O’Leary, Kylie S Dempster, Adam J MacNeil, Danielle S Molnar, Jennifer McGrath, John Cairney

BMJ Open Jul 2019, 9 (7) e030339; DOI: 10.1136/bmjopen-2019-030339
Trial summary and protocol for a phase II randomised placebo-controlled double-blinded trial of Interleukin 1 blockade in Acute Severe Colitis: the IASO trial
Martin Geoffrey Thomas, Carrie Bayliss, Simon Bond, Francis Dowling, James Galea, Vipul Jairath, Christopher Lamb, Christopher Probert, Elizabeth Timperley-Preece, Alastair Watson, Lynne Whitehead, John G Williams, Miles Parkes, Arthur Kaser, Tim Raine

BMJ Open Feb 2019, 9 (2) e023765; DOI: 10.1136/bmjopen-2018-023765
Selective citation in the literature on the hygiene hypothesis: a citation analysis on the association between infections and rhinitis
Bram Duyx, Miriam J E Urlings, Gerard M H Swaen, Lex M Bouter, Maurice P Zeegers

BMJ Open Feb 2019, 9 (2) e026518; DOI: 10.1136/bmjopen-2018-026518
Hypersegmented airway neutrophils and its association with reduced lung function in adults with obstructive airway disease: an exploratory study
Ravi Lokwani, Peter A B Wark, Katherine J Baines, Daniel Barker, Jodie L Simpson

BMJ Open Jan 2019, 9 (1) e024330; DOI: 10.1136/bmjopen-2018-024330
Bortezomib in antibody-mediated autoimmune diseases (TAVAB): study protocol for a unicentric, non-randomised, non-placebo controlled trial
Siegfried Kohler, Stefanie Märschenz, Ulrike Grittner, Tobias Alexander, Falk Hiepe, Andreas Meisel

BMJ Open Jan 2019, 9 (1) e024523; DOI: 10.1136/bmjopen-2018-024523

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